Table 4 The combined effect of vaginal bleeding and progesterone administration in early pregnancy on offspring outcomes

Very preterm (< 34 weeks of gestation)

 N (%)

47(0.7)

21(0.4)

3(0.8)

14(1.9)

9(1.3)

 Adjusted model I^*

1

1.69(0.49–5.78)

4.16(2.09–8.26)

2.73(1.24–6.05)

 Adjusted model II^a

1

1.74(0.51–5.98)

4.25(2.13–8.49)

2.79(1.26–6.18)

Preterm (< 37 weeks of gestation)

 N (%)

261(4.0)

155(3.2)

16(4.3)

52(7.0)

38(5.6)

 Adjusted model I^*

1

1.32(0.78–2.25)

2.18(1.57–3.02)

1.74(1.20–2.51)

 Adjusted model II^a

1

1.35(0.79–2.30)

2.21(1.59–3.07)

1.74(1.21–2.52)

SGA

 N (%)

430(6.5)

300(6.2)

25(6.7)

51(6.9)

54(8.0)

 Adjusted model I^*

1

1.17(0.77–1.80)

1.20(0.88–1.63)

1.44(1.06–1.96)

 Adjusted model II^b

1

1.19(0.77–1.82)

1.23(0.89–1.68)

1.46(1.07–1.98)

LBW

 N (%)

167(2.5)

94(2.0)

10(2.7)

32(4.3)

31(4.6)

 Adjusted model I^*

1

1.44(0.74–2.80)

2.30(1.52–3.45)

2.44(1.60–3.70)

 Adjusted model II^b

1

1.39(0.61–3.16)

1.15(0.65–2.01)

2.10(1.25–3.51)

WAZ < -1 at 12 months of age (n = 3181)

 N (%)

99(3.1)

67(2.9)

3(1.7)

13(3.6)

16(5.1)

 Adjusted model I^*

1

0.61(0.19–1.97)

1.27(0.69–2.34)

1.84(1.05–3.24)

 Adjusted model II^c

1

0.61(0.19–2.00)

1.11(0.60–2.13)

1.79(1.01–3.19)