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Table 3 Differences in NTD-related stillbirth and infant mortality with late ToPFA cases, Turkey, 2014–2019, (n = 3911)

From: Evaluation of neural tube defects from 2014 to 2019 in Turkey

Variables

Overall

Stillbirth and infant death

ToPFA

p

n

3911

3440

471

 

Gender (%)

   

0.160

 Female

62.9

63.0

62.2

 

 Male

36.7

36.7

36.9

 

 Unknown

0.4

0.3

0.8

 

Gestational age (week)

32.6 ± 5.8

33.7 ± 5.1

24.5 ± 3.4

< 0.001

Birthweight (gr)

1736 ± 996

1875 ± 971

731 ± 445

< 0.001

Maternal age (year)

28.5 ± 6.5

28.6 ± 6.5

27.9 ± 6.4

0.033

Maternal education (year)

5.6 ± 4.4

5.4 ± 4.3

8.1 ± 4.3

< 0.001

Paternal education (year)

6.9 ± 4.4

6.7 ± 4.4

8.5 ± 4.3

< 0.001

Household size

4.6 ± 2.7

4.7 ± 2.7

3.7 ± 1.9

< 0.001

Consanguineous marriage (%)

   

< 0.001

 Yes

22.8

24.6a

9.8b

 

 No

71.4

69.5a

85.6b

 

 Unknown

5.8

5.9a

4.7a

 

Miscarriage/stillbirth history (%)

   

0.002

 Yes

30.1

31.0a

23.8b

 

 No

64.8

63.8a

72.0b

 

 Unknown

5.1

5.2a

4.2a

 

Maternal smoking (%)

   

0.674

 Yes

6.3

6.2

7.2

 

 No

85.6

85.6

85.1

 

 Unknown

8.1

8.1

7.6

 

Pregnancy type (%)

   

0.118

 Normal

94.1

93.8

96.2

 

 Assisted reproductive technology

2.2

2.3

1.3

 

 Unknown

3.7

3.9

2.5

 

Parity(%)

   

0.006

 Nullipar

24.2

23.4a

30.1b

 

 Multipar

72.1

72.8a

66.7b

 

 Unknown

3.7

3.7a

3.2a

 

Number of antenatal care

5.9 ± 5.0

6.0 ± 5.1

5.7 ± 4.7

 0.341

Number of fetuses in the pregnancy (%)

   

< 0.001

 Singleton

91.9

91.3a

96.4b

 

 Twin/triplet

4.2

4.6a

1.1b

 

 Unknown

3.9

4.1a

2.5a

 

Delivery type (%)

   

< 0.001

 Vaginal delivery

44.3

39.4a

80.3b

 

 Cesarean section

50.8

55.7a

15.3b

 

 Unknown

4.9

5.0a

4.5a

 

Regions (%)

   

< 0.001

 West

27.5

24.7a

47.8b

 

 South

10.0

10.3a

7.9a

 

 Central

12.1

10.7a

22.3b

 

 North

4.0

3.3a

9.8b

 

 East

46.4

51.0a

12.3b

 
  1. NTD Neural tube defect, ToPFA Termination of pregnancy for fetal anomaly
  2. Values are column percentage or mean ± SD
  3. a,bDifferent letters in the same row are significant