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Table 1 Baseline characteristics of study population by treatment arm and malaria status in early pregnancy

From: The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries

Variable

ALL CALL COUNTRIES

LDA (N = 724)

PLACEBO (N = 722)

Malaria negative

Malaria positive

Malaria negative

Malaria positive

Randomized, N (%)

445 (61)

279 (39)

439 (61)

283 (39)

Maternal age (years), N (%)

   < 20

225 (50·6)

209 (74·9)

250 (56·9)

206 (72·8)

  20–29

214 (48·1)

69 (24·7)

185 (42·1)

74 (26·1)

   > 29

6 (1·3)

1 (0·4)

4 (0·9)

3 (1·1)

  Median (P25, P75)

19·0 (18·0, 22·0)

18·0 (17·0, 19·5)

19·0 (18·0, 21·0)

18·0 (17·0, 20·0)

Projected gestational age at enrollment (weeks, days), N (%)

 6, 0 – 7, 6

63 (14·2)

30 (10·8)

72 (16·4)

26 (9·2)

 8, 0 – 9, 6

134 (30·1)

75 (26·9)

114 (26·0)

76 (26·9)

 10, 0 – 10, 6

66 (14·8)

33 (11·8)

57 (13·0)

31 (11·0)

 11, 0 – 11,6

47 (10·6)

48 (17·2)

66 (15·0)

54 (19·1)

 12, 0 – 13, 6

135 (30·3)

93 (33·3)

130 (29·6)

96 (33·9)

 Median (P25, P75)

10·3 (8·7, 12·3)

11·0 (9·1, 12·4)

10·6 (8·4, 12·1)

11·1 (9·0, 12·4)

Maternal education, N (%)

 No formal

20 (4·5)

25 (9·0)

19 (4·3)

24 (8·5)

 Primary

58 (13·0)

84 (30·1)

60 (13·7)

97 (34·3)

 Secondary

334 (75·1)

158 (56·6)

327 (74·5)

156 (55·1)

 University + 

33 (7·4)

12 (4·3)

33 (7·5)

6 (2·1)

Maternal height (cm), N

 Mean (StdDev)

157·0 (7·5)

155·6 (8·0)

157·0 (7·4)

155·2 (7·9)

 Median (P25, P75)

158·0 (152·5, 162·0)

156·0 (150·2, 161·0)

157·0 (152·5, 161·9)

155·0 (150·0, 160·0)

Maternal weight (kg), N

 Mean (StdDev)

55·0 (8·1)

53·0 (7·4)

55·0 (8·3)

52·3 (7·5)

 Median (P25, P75)

54·0 (50·0, 59·0)

52·2 (48·0, 58·0)

54·0 (50·0, 60·0)

52·0 (47·0, 56·8)

Maternal BMI (kg/m2), N

 Mean (StdDev)

22·4 (3·4)

22·0 (3·1)

22·3 (3·4)

21·8 (3·1)

 Median (P25, P75)

21·1 (20·0, 24·0)

21·7 (19·7, 23·4)

21·9 (20·0, 24·1)

21.5 (19·5, 23·3)

Antenatal care visits, N

 Mean (StdDev)

4·2 (1·1)

3·9 (1·3)

4·2 (1·1)

3·9 (1·2)

 Median (P25, P75)

4·0 (4·0, 5·0)

4·0 (3·0, 5·0)

4·0 (4·0, 5·0)

4·0 (3·0, 5·0)

Delivery attendant, N (%)

 Physician

24 (5·4)

9 (3·2)

18 (4·1)

9 (3·2)

 Nurse/nurse midwife

391 (87·9)

241 (86·4)

383 (87·2)

239 (84·5)

 Traditional birth attendant

19 (4·3)

22 (7·9)

23 (5·2)

30 (10·6)

 Family/Self/Other

11 (2·5)

7 (2·5)

15 (3·4)

5 (1·8)

Delivery location, N (%)

 Hospital

113 (25·4)

58 (20·8)

122 (27·8)

46 (16·3)

 Clinic/health center

296 (66·5)

180 (64·5)

270 (61·5)

194 (68·6)

 Home/Other

36 (8·1)

41 (14·7)

47 (10·7)

43 (15·2)

Delivery mode, N (%)

 Vaginal

426 (95·7)

271 (97·1)

422 (96·1)

276 (97·5)

 C-section

19 (4·3)

8 (2·9)

17 (3·9)

7 (2·5)

Site, N (%)

 DRC

87 (19·6)

140 (50·2)

85 (19·4)

157 (55·5)

 Kenya

199 (44·7)

130 (46·6)

199 (45·3)

114 (40·3)

 Zambia

159 (35·7)

9 (3·2)

155 (35·3)

12 (4·2)