Table 1 Baseline characteristics of study population by treatment arm and malaria status in early pregnancy
From: The efficacy of low-dose aspirin in pregnancy among women in malaria-endemic countries
Variable | ALL CALL COUNTRIES | |||
|---|---|---|---|---|
LDA (N = 724) | PLACEBO (N = 722) | |||
Malaria negative | Malaria positive | Malaria negative | Malaria positive | |
Randomized, N (%) | 445 (61) | 279 (39) | 439 (61) | 283 (39) |
Maternal age (years), N (%) | ||||
< 20 | 225 (50·6) | 209 (74·9) | 250 (56·9) | 206 (72·8) |
20–29 | 214 (48·1) | 69 (24·7) | 185 (42·1) | 74 (26·1) |
> 29 | 6 (1·3) | 1 (0·4) | 4 (0·9) | 3 (1·1) |
Median (P25, P75) | 19·0 (18·0, 22·0) | 18·0 (17·0, 19·5) | 19·0 (18·0, 21·0) | 18·0 (17·0, 20·0) |
Projected gestational age at enrollment (weeks, days), N (%) | ||||
6, 0 – 7, 6 | 63 (14·2) | 30 (10·8) | 72 (16·4) | 26 (9·2) |
8, 0 – 9, 6 | 134 (30·1) | 75 (26·9) | 114 (26·0) | 76 (26·9) |
10, 0 – 10, 6 | 66 (14·8) | 33 (11·8) | 57 (13·0) | 31 (11·0) |
11, 0 – 11,6 | 47 (10·6) | 48 (17·2) | 66 (15·0) | 54 (19·1) |
12, 0 – 13, 6 | 135 (30·3) | 93 (33·3) | 130 (29·6) | 96 (33·9) |
Median (P25, P75) | 10·3 (8·7, 12·3) | 11·0 (9·1, 12·4) | 10·6 (8·4, 12·1) | 11·1 (9·0, 12·4) |
Maternal education, N (%) | ||||
No formal | 20 (4·5) | 25 (9·0) | 19 (4·3) | 24 (8·5) |
Primary | 58 (13·0) | 84 (30·1) | 60 (13·7) | 97 (34·3) |
Secondary | 334 (75·1) | 158 (56·6) | 327 (74·5) | 156 (55·1) |
University + | 33 (7·4) | 12 (4·3) | 33 (7·5) | 6 (2·1) |
Maternal height (cm), N | ||||
Mean (StdDev) | 157·0 (7·5) | 155·6 (8·0) | 157·0 (7·4) | 155·2 (7·9) |
Median (P25, P75) | 158·0 (152·5, 162·0) | 156·0 (150·2, 161·0) | 157·0 (152·5, 161·9) | 155·0 (150·0, 160·0) |
Maternal weight (kg), N | ||||
Mean (StdDev) | 55·0 (8·1) | 53·0 (7·4) | 55·0 (8·3) | 52·3 (7·5) |
Median (P25, P75) | 54·0 (50·0, 59·0) | 52·2 (48·0, 58·0) | 54·0 (50·0, 60·0) | 52·0 (47·0, 56·8) |
Maternal BMI (kg/m2), N | ||||
Mean (StdDev) | 22·4 (3·4) | 22·0 (3·1) | 22·3 (3·4) | 21·8 (3·1) |
Median (P25, P75) | 21·1 (20·0, 24·0) | 21·7 (19·7, 23·4) | 21·9 (20·0, 24·1) | 21.5 (19·5, 23·3) |
Antenatal care visits, N | ||||
Mean (StdDev) | 4·2 (1·1) | 3·9 (1·3) | 4·2 (1·1) | 3·9 (1·2) |
Median (P25, P75) | 4·0 (4·0, 5·0) | 4·0 (3·0, 5·0) | 4·0 (4·0, 5·0) | 4·0 (3·0, 5·0) |
Delivery attendant, N (%) | ||||
Physician | 24 (5·4) | 9 (3·2) | 18 (4·1) | 9 (3·2) |
Nurse/nurse midwife | 391 (87·9) | 241 (86·4) | 383 (87·2) | 239 (84·5) |
Traditional birth attendant | 19 (4·3) | 22 (7·9) | 23 (5·2) | 30 (10·6) |
Family/Self/Other | 11 (2·5) | 7 (2·5) | 15 (3·4) | 5 (1·8) |
Delivery location, N (%) | ||||
Hospital | 113 (25·4) | 58 (20·8) | 122 (27·8) | 46 (16·3) |
Clinic/health center | 296 (66·5) | 180 (64·5) | 270 (61·5) | 194 (68·6) |
Home/Other | 36 (8·1) | 41 (14·7) | 47 (10·7) | 43 (15·2) |
Delivery mode, N (%) | ||||
Vaginal | 426 (95·7) | 271 (97·1) | 422 (96·1) | 276 (97·5) |
C-section | 19 (4·3) | 8 (2·9) | 17 (3·9) | 7 (2·5) |
Site, N (%) | ||||
DRC | 87 (19·6) | 140 (50·2) | 85 (19·4) | 157 (55·5) |
Kenya | 199 (44·7) | 130 (46·6) | 199 (45·3) | 114 (40·3) |
Zambia | 159 (35·7) | 9 (3·2) | 155 (35·3) | 12 (4·2) |