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Table 3 Obstetric complications and outcome of pregnancies in patients with different degree of AVB

From: Pregnancy maternal fetal outcomes among pregnancies complicated with atrioventricular block

Complications and Outcome

No(%)

(M=74/F=76)a

I° AVB

(M=16/F=17)

II° AVB(n=25)

III° AVB

(n=33)

p-value

Type I (M=18/F19)

Type II (n=7)

Fetal complications

 Prematurity

11 (14.47)

1 (5.88)

6 (31.58)

1 (14.29)

3 (9.09)

0.116

 SGA

2 (2.63)

0

1 (5.26)

1 (14.29)

0

0.099

 Fetal distress

1 (1.32)

0

0

0

1 (3.03)

1.000

 Oligohydramnios

2 (2.63)

1 (5.88)

1 (5.26)

0

0

0.398

Maternal complications

 PROM

3 (4.05)

1 (6.25)

0

0

2 (6.06)

0.707

 GDM

3 (4.05)

0

1 (5.56)

0

2 (6.06)

1.000

 MCDA

2 (2.70)

1 (6.25)

1 (5.56)

0

0

0.389

 Preeclampsia

1 (1.35)

0

0

0

1 (3.03)

1.000

 Placental adhesion

6 (8.11)

0

3 (16.67)

1 (14.29)

2 (6.06)

0.220

 Velamentous placenta

1 (1.35)

0

1 (5.56)

0

0

0.554

 Thrombocytopenia in pregnancy

3 (4.05)

1 (6.25)

1 (5.56)

0

1 (3.03)

1.000

 proteinuria + pedal edema

1 (1.35)

0

0

1 (14.29)

0

0.095

Mode of delivery

 Caesarean section

60 (81.08)

10 (62.5)

12 (66.67)

7 (100)

31 (93.94)

0.009#

 Vaginal delivery

14 (18.92)

6 (37.5)

6 (33.33)

0

2 (6.06)

Fetal cardiac abnormalities

 Fetal TR

1 (1.32)

1 (5.89)

0

0

0

0.316

1.000

 Fetal VSD

2 (2.63)

0

1 (5.26)

0

1 (3.03)

 Transfer to ICU

4 (5.45)

1 (6.25)

0

2 (28.57)

1 (3.03)

0.053

 Transfer to cardiology

2 (2.70)

0

0

0

2 (6.06)

0.780

 Neonatal death

0

0

0

0

0

-

 Maternal death

0

0

0

0

0

-

 Postpartum hemorrhage

3 (4.05)

0

0

1 (14.29)

2 (6.06)

0.289

Mean neonatal weight (kg)

76

3148.23±435.93(n=17)

3101.05±531.61(n=19)

3278.57±545.81

3026.21±320.23

0.479

HOD (day)

74

4.37±1.14

4.44±1.14

5.28±1.60

4.87±0.89

0.160

Blood loss during delivery (ml)

74

353.12±88.44

511.11±234.86

507.14±73.19

575.75±167.29

0.001

  1. M Maternal, F Fetal, SGA Small for gestational age, PROM Premature rupture of membranes, GDM Gestational diabetes mellitus, MCDA Monochorionic diamnionic twin, TR Tricuspid Regurgitation, VSD Ventricular septal defect, ICU Intensive care unit, HOD Hospital day (total days of hospital stay)
  2. aTotal number of fetuses was 76 because there are two patients with twin pregnancies (maternal number = 74); *Two case with fetal heart hyperechoic both have been checked by high-throughput genome sequencing, and showed no abnormality in prenatal screening;
  3. #Multiple test results: comparison of I ° AVB and III ° AVB, p = 0.017; Type I AVB and III ° AVB, p= 0.031
  4. Multiple test results: comparison of I ° AVB and type I AVB, p = 0.008; I ° AVB and type II AVB p = 0.047; I ° AVB and III ° AVB, p= 0.000