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Table 3 Threshold effect analysis of E2 level (100pg/mL) in cycles with lower E2 level (< 1400 pg/mL)

From: The relationship between serum oestrogen levels and clinical outcomes of hormone replacement therapy-frozen embryo transfer: a retrospective clinical study

Outcome

Clinical pregnancy

Model I (linear)

OR

95% CI

p value

Linear effect

0.970

(0.950, 0.990)

0.004

Model II (polyline)

OR

95% CI

p value

Predicted threshold (K, E 2 level, 100pg/mL)

3

Effect 1 (< K)

1.074

(1.000, 1.153)

0.051

Effect 2 (> K)

0.944

(0.919, 0.970)

< 0.001

variability of effectiveness

0.572

(0.499, 0.646)

 

Logarithmic likelihood ratio test

0.004

  1. When the E2 level was between 300 to 1400 pg/mL, there was a negative relationship between E2 levels and the clinical pregnancy rate
  2. E2 oestrogen, OR odds ratio, CI confidence interval, K predicted threshold