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Table 3 Cox proportional hazard ratio of the association between combinations of pregnancy complications and subsequent maternal CVD

From: Prior pregnancy complications and maternal cardiovascular disease in young Korean women within 10 years after pregnancy

 

Unadjusted HR

Adjusted HRa

HR

95% CI

HR

95% CI

Total CVD

 No complications

1

 

1

 

 PE or LBW or PTD

1.31

1.23, 1.38

1.27

1.20, 1.35

 PE + LBW

1.38

1.07, 1.79

1.29

1.00, 1.67

 PE + PTD

2.46

1.73, 3.49

2.23

1.57, 3.17

 LBW + PTD

1.22

1.10, 1.36

1.19

1.07, 1.33

 PE + LBW + PTD

2.21

1.89, 2.58

2.06

1.76, 2.40

IHD

 No complications

1

 

1

 

 PE or LBW or PTD

1.33

1.24, 1.43

1.28

1.20, 1.38

 PE + LBW

1.50

1.08, 2.09

1.38

0.99, 1.91

 PE + PTD

2.57

1.64, 4.04

2.28

1.45, 3.58

 LBW + PTD

1.25

1.08, 1.44

1.21

1.04, 1.39

 PE + LBW + PTD

2.62

2.17, 3.16

2.39

1.98, 2.89

Stroke

 No complications

1

1

1

 

 PE or LBW or PTD

1.27

1.17, 1.38

1.25

1.15, 1.35

 PE + LBW

1.33

0.08, 1.93

1.26

0.86, 1.83

 PE + PTD

2.90

1.83, 4.61

2.70

1.70, 4.29

 LBW + PTD

1.26

1.08, 1.47

1.23

1.05, 1.43

PE + LBW + PTD

1.74

1.35, 2.23

1.64

1.28, 2.10

  1. CI confidence interval, CVD cardiovascular disease, HR hazard ratio, PE preeclampsia, LBW low birth weight, PTD preterm delivery, IHD ischemic heart disease
  2. aAdjusted for maternal age, BMI, systolic BP, diastolic BP, aspartate aminotransferase, alanine aminotransferase, fasting glucose, total cholesterol, and smoking