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Table 1 Demographic data and clinical chemistry test results for the enrolled pregnant women and the newborns in the present study

From: Cord blood metabolomics reveals gestational metabolic disorder associated with anti-thyroid peroxidase antibodies positivity

Item

Control group

(mean ± s.d.)

Anti-TPO antibodies positivity group

(mean ± s.d.)

p-value

Age (year)

29.42 ± 2.17

30.09 ± 3.08

0.26

BMI of the pregnant women (Kg/m2)

26.29 ± 2.74

26.27 ± 3.48

0.76

Fetus number (singleton/multiple pregnancies)

6/5

9/2

0.18 (χ2 = 2.93)*

gestational weeks of delivery

38.85 ± 0.95

38.91 ± 0.83

0.69

TSH (μIU/ml)

2.20 ± 0.37

2.28 ± 0.32

0.91

FT3 (pmol/L)

4.78 ± 0.47

4.85 ± 0.48

0.48

FT4 (pmol/L)

15.59 ± 2.10

16.47 ± 2.57

0.30

anti-TPO antibodies (IU/ml)

15.11 ± 4.16

273.70 ± 168.50

0.00047

FBG in the 11th gestational week (mmol/L)

4.65 ± 0.19

5.18 ± 0.69

0.06

FBG at delivery (mmol/L)

4.44 ± 0.32

4.91 ± 0.60

0.09

Gender of the newborns (Male/Female)

5/6

6/5

0.39 (χ2 = 0.78)#

Birthweight of the newborns (Kg) (Q1, Q2, Q3)a

3.32 ± 0.35

(3.17, 3.38, 3.51)

3.14 ± 0.21

(3.02, 3.09, 3.27)

0.52

  1. BMI body mass index, TSH thyroid stimulating hormone, FT3 free triiodothyronine, FT4 free thyroxine, FBG fasting blood glucose
  2. aThe distribution of newborn weight was expressed by the first Quartile (Q1), the second Quartile (Q2), and the third Quartile (Q3)
  3. *, # The differences of fetus number* and newborn gender# between the case and the control group were tested by the chi-square test, respectively