Skip to main content

Table 3 Chromosomal abnormalities in 87 cases

From: Evaluation of prenatal central nervous system anomalies: obstetric management, fetal outcomes and chromosome abnormalities

Types of CNS anomalies Normal karyotype (n, %) Abnormal karyotype     
   Patau (n, %) Edward (n, %) Down (n, %) Turner (n, %) Miscellaneous (n, %)
Neural tube defect
 - Anencephaly - - - - - -
 - Encephalocele 4 (4.60) - 1 (1.15) - - -
 -Meningocele 1 (1.15) - - - - -
 -Myelomeningocele 2 (2.30) 1 (1.15) - - - -
 -Spina bifida occulta - - - - - -
 - Unclassified closed spina bifida 3 (3.45) - - - - -
 -Unclassified NTD - - - - - -
Ventriculomegaly 24 (27.59) 4 (4.60) 5 (5.75) 5 (5.75) - 3 (3.45)
Holoprosencephaly 7 (8.05) 7 (8.05) 3 (3.45) - - 1 (1.15)
Microcephaly 2 (2.30) 2 (2.30) - 1 (1.15) - -
Cysts
 - arachnoid cyst 1 (1.15) 1 (1.15) - - - -
 - choroid plexus cyst - - 6 (6.90) 1 (1.15) - -
Cystic hygroma 7 (8.05) 1 (1.15) - - 5 (5.75) -
Chiari Type II malformation 2 (2.30) - 1 (1.15) - - -
Dandy Walker malformation 5 (5.75) 4 (4.60) 4 (4.60) - - -
Cerebellar disorder 5 (5.75) 1 (1.15) - 1 (1.15) - -
Megacisterna magna 3 (3.45) - 6 (6.90) - - 1 (1.15)
Agenesis of corpus callosum (ACC) 2 (2.30) 1 (1.15) - 1 (1.15) - -
Other spinal malformations 7 (8.05) 1 (1.15) - - - -
Miscellaneous
 -sacrococcygeal teratoma - - - - - -
 -cerebral atrophy - - - - - -
 -wide CSP - - 1 (1.15) - - -
 -absent CSP 1 (1.15) - 2 (2.30) - - -
 -megalencephaly - - - - - -
 -hydranencephaly - - - - - -
 -intracranial haemorrhage - - - - - -
 -intracranial tumour - - - - - -