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Table 1 Characteristics of women with positive antithyroid antibodies

From: IVF/ICSI outcomes of euthyroid infertile women with thyroid autoimmunity: does treatment with aspirin plus prednisone matter?

Cycles

Fresh embryo transfer cycles

Frozen-thawed embryo transfer cycles

Control group n = 113

P + A group n = 74

P value

Control group n = 83

P + A group n = 76

P value

Age (yrs.)

31.0 (29.0-35.0)

31.5 (29.0-35.0)

0.832

30.0 (28.0-34.0)

30.0 (28.0-34.8)

0.737

<31

44 (38.9%)

26 (35.1%)

0.829

44 (53.0%)

39 (51.3%)

0.727

31-37

63 (55.8%)

43 (58.1%)

35 (42.2%)

31 (40.8%)

>37

6 (5.3%)

5 (6.8%)

4 (4.8%)

6 (7.9%)

BMI (kg/m2)

22.0 (20.0-24.0)

22.3 (20.2-25.1)

0.336

22.38 ± 2.97

22.09 ± 3.26

0.557

BMI≥25 (kg/m2)

21 (18.6%)

21 (28.4%)

0.117

16 (19.3%)

14 (18.4%)

0.890

Previous miscarriages

0.0 (0.0-1.0)

1.0 (0.0-1.0)

0.636

0.0 (0.0-1.0)

0.0 (0.0-1.0)

0.752

≥2

21 (18.6%)

15 (20.3%)

0.775

7 (8.4%)

10 (13.2%)

0.336

Duration of infertility (yrs.)

3.0 (2.0-5.5)

3.0 (1.0-5.0)

0.961

3.0 (1.3-4.0)

2.0 (2.0-4.0)

0.973

<3

53 (46.9%)

32 (43.2%)

0.623

39 (47.0%)

40 (52.6%)

0.477

≥3

60 (53.1%)

42 (56.8%)

44 (53.0%)

36 (47.4%)

Primary infertility

50 (44.2%)

30 (40.5%)

0.616

42 (50.6%)

35 (46.1%)

0.566

Basal FSH (IU/L)

5.74 ± 1.57

5.67 ± 1.36

0.732

6.2 (4.7-7.1)

5.2 (4.4-6.3)

0.094

AMH (ng/mL)

2.7 (1.7-3.7)

2.9 (1.9-4.2)

0.429

4.3 (2.4-6.5)

3.9 (1.9-6.0)

0.327

AFC

11.0 (7.0-18.0)

14 (10.0-17.0)

0.103

12.0 (9.0-18.0)

14.0 (8.0-17.0)

0.882

TSH (mIU/L)

2.2 (1.5-2.8)

2.0 (1.4-2.7)

0.422

2.22 ± 0.90

1.99 ± 0.86

0.109

FT4 (ng/dL)

1.00 ± 0.14

1.01 ± 0.09

0.475

1.0 (0.9-1.1)

1.0 (1.0-1.1)

0.867

FT3 (pg/mL)

3.05 ± 0.44

2.90 ± 0.39

0.017a

2.99 ± 0.48

2.89 ± 0.39

0.145

Only TPOAb positivity

9 (8.0%)

7 (9.5%)

0.542

9 (10.8%)

12 (15.8%)

0.592

Only TgAb positivity

52 (46.0%)

28 (37.8%)

33 (39.8%)

31 (40.8%)

Both positivity

52 (46.0%)

39 (52.7%)

41 (49.4%)

33 (43.4%)

  1. P < 0.05 was considered statistically significant. a represents a statistically significant difference between the two groups
  2. Continuous data are expressed as mean±SD when normally distributed, or as median (25th -75th ) otherwise. Categorical variables are expressed as number and percentage
  3. BMI body mass index, FSH follicle-stimulating hormone, AMH anti-Mullerian hormone, AFC antral follicle count, TSH thyroid-stimulating hormone, FT4 free thyroxine, FT3 free triiodothyronine, TPOAb anti-thyroperoxidase antibody, TgAb thyroglobulin antibody
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