Table 2 Cycle characteristics and embryo parameters grouped by blastomere number
From: Increased blastomere number is associated with higher live birth rate in day 3 embryo transfer
≤ 6-cell (n = 100) | 7-cell (n = 207) | 8-cell (n = 1522) | 9-cell (n = 187) | 10-cell (n = 91) | ≥ 11-cell (n = 130) | P-value | |
|---|---|---|---|---|---|---|---|
Cycle characteristics | |||||||
Duration of stimulation (days) | 11 (9, 13) | 11 (10, 13) | 11 (10, 13) | 11 (10, 12) | 11 (10, 12) | 11 (10, 12) | 0.497 |
Total gonadotropin dose (IU) | 2700 (2025, 3713) | 2675 (1875, 3525) | 2250 (1650, 3000) | 2400 (1575, 3300) | 2475 (1732, 3225) | 2175 (1650, 2850) | < 0.001 |
LH level at trigger day (mIU/mL) | 0.8 (0.6, 1.5) | 0.8 (0.6, 1.3) | 0.9 (0.6, 1.3) | 0.9 (0.6, 1.3) | 0.9 (0.6, 1.4) | 0.9 (0.6, 1.3) | 0.985 |
E2 level at trigger day (pg/mL) | 1087.5 (663.1, 1859.0) | 1360.0 (798.0, 1985.0) | 1637.8 (1070.0, 2329.0) | 1360.0 (818.0, 2134.0) | 1374.4 (849.7, 2126.0) | 1408.2 (950.7, 2086.4) | < 0.001 |
P level at trigger day (ng/mL) | 0.6 (0.3, 0.8) | 0.6 (0.4, 0.9) | 0.6 (0.4, 0.9) | 0.5 (0.3, 0.8) | 0.6 (0.4, 0.9) | 0.6 (0.4, 0.8) | 0.009 |
Endometrial thickness at trigger day (mm) | 10.3 (9.0, 12.2) | 10.4 (8.7, 12.2) | 10.6 (9.0, 12.3) | 10.3 (8.8, 12.2) | 10.2 (8.5, 11.6) | 11.0 (9.0, 12.9) | 0.130 |
No. of oocytes retrieved | 7 (4, 8) | 7 (4, 10) | 10 (7, 13) | 8 (5, 12) | 8 (5, 11) | 9 (6,12) | < 0.001 |
Fertilization method, n (%) | 0.005 | ||||||
IVF | 74 (74.0) | 138 (66.7) | 1194 (78.4) | 143 (76.5) | 71 (78.0) | 107 (82.3) | |
ICSI | 26 (26.0) | 69 (33.3) | 329 (21.6) | 44 (23.5) | 20 (22.0) | 23 (17.7) | |
Embryo parameters | |||||||
Fragmentation percentage, n (%) | < 0.001 | ||||||
< 10% | 14 (14.0) | 28 (13.5) | 224 (14.7) | 54 (28.9) | 21 (23.1) | 32 (24.6) | |
10–20% | 67 (67.0) | 156 (75.4) | 1244 (81.7) | 131 (70.0) | 69 (75.8) | 98 (75.4) | |
> 20% | 19 (19.0) | 23 (11.1) | 54 (3.6) | 2 (1.1) | 1 (1.1) | 0 (0) | |
Blastomere symmetry, n (%) | < 0.001 | ||||||
Even | 74 (74.0) | 150 (72.5) | 1418 (93.2) | 106 (56.7) | 60 (65.9) | 89 (68.5) | |
Uneven | 26 (26.0) | 57 (27.5) | 104 (6.8) | 81 (43.3) | 31 (34.1) | 41 (31.5) | |
Multinucleation or vacuoles, n (%) | 1 (1.0) | 2 (1.0) | 23 (1.5) | 2 (1.1) | 1 (1.1) | 0 (0) | 0.889 |