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Table 5 Logistic regression analysis on the contribution of the potential predicting variables to live birth and clinical pregnancy outcomes of PCOS patients

From: Association of antimüllerian hormone with polycystic ovarian syndrome phenotypes and pregnancy outcomes of in vitro fertilization cycles with fresh embryo transfer

Variables

Live birth

Clinical pregnancy

OR (95% CI)

P-value

Adjusted OR

(95% CI)a

P-valuea

OR (95% CI)

P-value

Adjusted OR

(95% CI)a

P-valuea

Group

 Low-AMH

1.440 (0.830–2.500)

0.195

1.370 (0.750–2.502)

0.306

1.123 (0.627–2.012)

0.696

1.016 (0.544–1.901)

0.959

 Average-AMH

1.147 (0.713–1.845)

0.571

1.045 (0.630–1.734)

0.863

1.318 (0.790–2.199)

0.290

1.225 (0.717–2.093)

0.459

 High-AMH

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Female age (y)

0.955 (0.904–1.009)

0.098

0.928 (0.872–0.986)

0.017

0.957 (0.902–1.016)

0.149

0.934 (0.875–0.998)

0.043

Female BMI (kg/m2)

1.002 (0.996–1.007)

0.583

  

1.003 (0.980–1.026)

0.809

  

Duration of infertility (y)

0.985 (0.912–1.063)

0.696

  

1.000 (0.920–1.087)

0.999

  

Total dose of gonadotropin used (IU)1

1.035 (0.802–1.335)

0.794

  

1.100 (0.828–1.460)

0.511

  

Serum E2 level (pg/mL) on hCG day2

1.212 (1.066–1.379)

0.003

  

1.103 (0.963–1.263)

0.158

  

Endometrial thickness (mm) on hCG day

1.104 (1.008–1.209)

0.034

1.094 (0.990–1.208)

0.077

1.078 (0.977–1.191)

0.135

1.064 (0.958–1.183)

0.248

No. of oocyte fertilized

1.054 (1.002–1.108)

0.042

1.014 (0.960–1.071)

0.626

1.057 (1.001–1.117)

0.046

1.011 (0.954–1.071)

0.711

No. of embryos transferred

0.907 (0.591–1.391)

0.654

1.916 (1.094–3.358)

0.023

0.860 (0.538–1.373)

0.527

1.871 (1.007–3.476)

0.048

Embryo type

 Cleavage embryo

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 Blastocyst

2.747 (1.812–4.164)

 < 0.001

3.488 (2.023–6.013)

 < 0.001

2.790 (1.742–4.468)

 < 0.001

3.659 (1.970–6.795)

 < 0.001

Embryo quality

 Cycle with high-quality embryos

Ref

Ref

Ref

Ref

Ref

Ref

Ref

Ref

 Cycles without high-quality embryos

0.158 (0.034–0.742)

0.019

0.172 (0.035–0.841)

0.030

0.332 (0.099–1.110)

0.073

0.423 (0.120–1.488)

0.180

  1. Note: All the variables inputted in the model were shown in Table 5. BMI Body mass index, CI Confidence interval, OR Odds ratio, E2 Estradiol, hCG human chorionic gonadotropin, Ref Reference, 1 per 1000 IU increased, 2 per 1000 pg/mL increased
  2. aAdjusted for maternal age, endometrial thickness on the day of ovulatory dose of hCG, number of fertilization, number of embryos transferred, embryo type and embryo quality