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Table 2 General baseline data comparison [n(%), mean ± SD]

From: Expression and clinical significance of miR-204 in patients with hypertensive disorder complicating pregnancy

Parameters

HDCP (n = 196)

Control (n = 54)

χ2/t

P

Mean age (years)

33.45 ± 3.07

32.74 ± 3.12

1.5

0.135

Pre-pregnancy BMI (kg/m2)

22.51 ± 2.03

22.14 ± 1.97

1.193

0.234

Gravidity (times)

2.31 ± 0.28

2.25 ± 0.24

1.436

0.152

Parity (times)

2.01 ± 0.19

1.98 ± 0.14

1.082

0.281

Systolic pressure (mmHg)

157.79 ± 13.05

114.63 ± 10.08

22.51

 < 0.001

Diastolic pressure (mmHg))

101.34 ± 8.76

73.26 ± 7.14

21.65

 < 0.001

Fasting blood glucose (mmol/L)

4.75 ± 0.23

4.68 ± 0.49

1.494

0.136

ALT (U/L)

19.12 ± 1.58

12.16 ± 1.61

28.55

 < 0.001

AST (U/L)

32.27 ± 3.15

22.04 ± 2.19

22.4

 < 0.001

LDH (U/L)

188.24 ± 12.75

153.19 ± 11.08

18.37

 < 0.001

PLT (× 109/L)

208.81 ± 20.57

204.16 ± 20.03

1.479

0.14

24-h urinary protein (mg/L)

249.72 ± 10.36

109.64 ± 10.05

88.54

 < 0.001

TNF-α (pg/mL)

20.82 ± 2.16

8.75 ± 0.91

40.05

 < 0.001

IL-6 (pg/mL)

156.05 ± 15.28

94.61 ± 9.12

28.17

 < 0.001

hs-CRP (mg/L)

6.46 ± 0.43

4.53 ± 0.27

31.3

 < 0.001

Family history of HDCP

 

-

-

-

 Yes

79 (40.31)

-

-

-

 No

117 (59.69)

-

-

-

Disease type (n/%)

 

-

-

-

 Mild preeclampsia

76 (38.78)

-

-

-

 Severe preeclampsia

62 (31.63)

-

-

-

 HDCP

58 (29.59)

-

-

-

  1. n(%), number of cases and percentage; mean ± SD, mean ± standard deviation; HDCP Hypertensive disorder complicating pregnancy, BMI Body mass index, ALT Alanine aminotransferase, AST Aspartate aminotransferase, LDH Lactate dehydrogenase, PLT Platelet count, TNF-α Tumor necrosis factor-α, IL-6 Interleukin-6, hs-CRP High-sensitivity C-reactive protein