Parameters | HDCP (n = 196) | Control (n = 54) | χ2/t | P |
---|---|---|---|---|
Mean age (years) | 33.45 ± 3.07 | 32.74 ± 3.12 | 1.5 | 0.135 |
Pre-pregnancy BMI (kg/m2) | 22.51 ± 2.03 | 22.14 ± 1.97 | 1.193 | 0.234 |
Gravidity (times) | 2.31 ± 0.28 | 2.25 ± 0.24 | 1.436 | 0.152 |
Parity (times) | 2.01 ± 0.19 | 1.98 ± 0.14 | 1.082 | 0.281 |
Systolic pressure (mmHg) | 157.79 ± 13.05 | 114.63 ± 10.08 | 22.51 | < 0.001 |
Diastolic pressure (mmHg)) | 101.34 ± 8.76 | 73.26 ± 7.14 | 21.65 | < 0.001 |
Fasting blood glucose (mmol/L) | 4.75 ± 0.23 | 4.68 ± 0.49 | 1.494 | 0.136 |
ALT (U/L) | 19.12 ± 1.58 | 12.16 ± 1.61 | 28.55 | < 0.001 |
AST (U/L) | 32.27 ± 3.15 | 22.04 ± 2.19 | 22.4 | < 0.001 |
LDH (U/L) | 188.24 ± 12.75 | 153.19 ± 11.08 | 18.37 | < 0.001 |
PLT (× 109/L) | 208.81 ± 20.57 | 204.16 ± 20.03 | 1.479 | 0.14 |
24-h urinary protein (mg/L) | 249.72 ± 10.36 | 109.64 ± 10.05 | 88.54 | < 0.001 |
TNF-α (pg/mL) | 20.82 ± 2.16 | 8.75 ± 0.91 | 40.05 | < 0.001 |
IL-6 (pg/mL) | 156.05 ± 15.28 | 94.61 ± 9.12 | 28.17 | < 0.001 |
hs-CRP (mg/L) | 6.46 ± 0.43 | 4.53 ± 0.27 | 31.3 | < 0.001 |
Family history of HDCP | - | - | - | |
Yes | 79 (40.31) | - | - | - |
No | 117 (59.69) | - | - | - |
Disease type (n/%) | - | - | - | |
Mild preeclampsia | 76 (38.78) | - | - | - |
Severe preeclampsia | 62 (31.63) | - | - | - |
HDCP | 58 (29.59) | - | - | - |