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Table 1 Baseline and treatment characteristics of patients stratified by the different trigger methods

From: Effect of GnRH agonist alone or combined with different low-dose hCG on cumulative live birth rate for high responders in GnRH antagonist cycles: a retrospective study

 

Group A:

0.2 mg GnRHa

Group B:

0.2 mg GnRHa+ 1000 IU hCG

Group C:

0.2 mg GnRHa + 2000 IU hCG

p

Cycles (n)

577

403

363

 

Female age (year)

29.63 ± 3.61

29.78 ± 3.65

30.06 ± .379

0.226

BMI (kg/m2)

21.92 ± 3.54

22.16 ± 3.64

22.39 ± 3.47

0.136

Duration of infertility (years)

4.03 ± 2.59

4.19 ± 2.50

4.19 ± 2.54

0.509

AMH (ng/ml)

9.70 ± 3.76

9.52 ± 4.11

9.31 ± 4.40

0.343

Basal FSH (IU/L)

5.42 ± 2.28

5.49 ± 2.26

5.45 ± 2.27

0.347

Previous IVF/ICSI cycles

   

0.970

 0

87.0 (502/577)

85.36 (344/403)

86.78 (315/363)

 

 1

10.57 (61/577)

11.41 (46/403)

10.19 (37/363)

 

 2

2.08 (12/577)

2.48 (10/403)

2.48 (9/363)

 

  ≥ 3

0.35 (2/577)

0.75 (3/403)

0.55 (2/363)

 

Type of infertility

   

0.799

 Primary infertility

57.71 (333/577)

57.82 (233/403)

59.78 (217/363)

 

 Secondary infertility

42.29 (244/577)

42.18 (170/403)

40.22 (146/363)

 

 Duration of stimulation (days)

9.73 ± 1.68

9.73 ± 1.95

9.63 ± 1.63

0.656

 Total dose of Gn (IU)

1539.37 ± 583.89

1541.69 ± 599.37

1561.19 ± 584.42

0.548

 E2 Levels at trigger day (pmol/ml)

16,896.28 ± 3052.42

16,797.20 ± 2944.31

16,725.54 ± 3094.00

0.608

 LH Levels at trigger day (IU/L)

1.79 ± 1.35

1.69 ± 1.35

1.71 ± 1.44

0.529

 P Levels at trigger day (nmol/ml)

3.50 ± 1.68

3.46 ± 1.72

3.42 ± 1.69

0.798

 No. of oocytes retrieved

22.93 ± 5.40

22.41 ± 5.25

22.69 ± 5.93

0.346

 Oocyte maturation rate (%)

82.92 (1850/2231)

81.42 (1030/1265)

81.21 (869/1070)

0.369

 Fertilization rate (%)

79.10 (10,157/12841)

79.0 (6946/8792)

78.78 (6323/8026)

0.860

 Cleavage rate (%)

98.62 (10,017/10157)

98.23 (6823/6946)

98.48 (6227/6323)

0.121

 2PN rate (%)

62.46 (8021/12841)

62.28 (5476/8792)

63.14 (5068/8026)

0.474

 Available day 3 embryo rate (%)

56.07 (5617/10017)

57.01 (3890/6823)

56.50 (3518/6227)

0.483

 Top-quality day 3 embryos rate (%)

20.33 (2036/10017)

20.75 (1416/6823)

20.06 (1249/6227)

0.606

 Moderate to severe OHSS rate (%)

0 (0/577)

1.49 (6/403)

1.38 (5/363)

0.002

 Unavailable embryo rate (%)

1.73 (10/577)

2.73 (11/403)

2.20 (8/363)

0.571