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Table 1 Development and utility of 0PN embryos divided by cell number on day 3

From: Does the cell number of 0PN embryos on day 3 affect pregnancy and neonatal outcomes following single blastocyst transfer?

 

0PN

2PN

P-Value

No. of zygotes (n)

46,804

232,441

/

Cleavage rate (%)

25.9 (12,114/46804)

97.4 (226,294/232441)

 < 0.001

 < 6 cells (%)

61.5 (7450/12114)

29.7 (67,261/226294)

 

 ≥ 6 cells (%)

38.5 (4664/12114)

70.3 (159,033/226294)

 

No. of embryos into blastocyst culture (n)

11,461

120,430

/

Available blastocyst rate, ABR (%)

13.9 (1595/11461)

23.4 (28,190/120,430)

 < 0.001

  < 6 cells (%)

2.5 (182/7287)

12.7 (8145/64359)

 < 0.001

  Day 5 (%)

14.3 (26/182)

12.6 (1023/8145)

0.488

  Day 6 (%)

85.7 (156/182)

87.4 (7122/8145)

  ≥ 6 cells (%)

33.9 (1413/4174)

35.7 (20,045/56071)

0.014

  Day 5 (%)

43.5 (615/1413)

27.0 (5409/20045)

 < 0.001

  Day 6 (%)

56.5 (798/1413)

73.0 (14,636/20045)

  1. 0PN Nonpronuclear, 2PN Two pronuclei