Exposure | Exposure category | N | N cases (%) | Unadjusted RR (95% CI), p-value | Adjusted RR (95% CI) a, p-value | Adjusted RR (95% CI) b, p-value |
---|---|---|---|---|---|---|
Body-mass index | Underweight | 1412 | 278 (19.7) | 1.06 (0.94, 1.20), 0.3 | 1.05 (0.93, 1.19), 0.4 | 1.05 (0.93, 1.19), 0.4 |
Normal weight | 15,383 | 2918 (19.0) | Ref | Ref | Ref | |
Overweight | 6140 | 1253 (20.4) | 1.06 (1.00, 1.14), 0.07 | 1.04 (0.97, 1.10), 0.3 | 1.04 (0.97, 1.10), 0.3 | |
Obese | 3657 | 868 (23.7) | 1.24 (1.15, 1.34), < 0.001 | 1.15 (1.07, 1.24), < 0.001 | 1.16 (1.08, 1.25), < 0.001 | |
Smoking | Never smoker | 14,267 | 2749 (19.3) | Ref | Ref | Ref |
Former smoker | 6400 | 1326 (20.7) | 1.09 (1.02, 1.16), 0.01 | 0.98 (0.93, 1.05), 0.6 | 0.97 (0.91, 1.03), 0.3 | |
< 10 cigarettes per day | 2247 | 442 (19.7) | 1.09 (0.98, 1.20), 0.1 | 0.98 (0.88, 1.08), 0.6 | 0.96 (0.87, 1.06), 0.4 | |
10–19 cigarettes per day | 1746 | 397 (22.7) | 1.27 (1.14, 1.41), < 0.001 | 1.09 (0.98, 1.21), 0.1 | 1.06 (0.95, 1.18), 0.3 | |
20 or more cigarettes per day | 1120 | 244 (21.8) | 1.23 (1.09, 1.39), 0.001 | 1.02 (0.90, 1.16), 0.7 | 0.99 (0.87, 1.13), 0.9 | |
Unknown amount of smoking | 812 | 159 (19.6) | 1.17 (1.01, 1.35), 0.04 | 1.04 (0.89, 1.22), 0.6 | 1.02 (0.86, 1.20), 0.8 | |
Alcohol intake | Low risk drinker | 22,612 | 4544 (20.1) | Ref | Ref | Ref |
Non-drinker | 2898 | 513 (17.7) | 0.83 (0.76, 0.92), < 0.001 | 0.84 (0.77, 0.92), < 0.001 | 0.83 (0.76, 0.91), < 0.001 | |
Risky drinker | 1082 | 260 (24.0) | 1.27 (1.13, 1.42), < 0.001 | 1.13 (1.01, 1.27), 0.03 | 1.13 (1.01, 1.27), 0.04 |