Exposure | Exposure category | N | N cases (%) | Unadjusted RR (95% CI), p-value | Adjusted RR (95% CI)a, p-value | Adjusted RR (95% CI)b, p-value |
---|---|---|---|---|---|---|
Body-mass index | Underweight | 1204 | 278 (23.1) | 1.08 (0.96, 1.22), 0.2 | 1.07 (0.94, 1.21), 0.3 | 1.07 (0.94, 1.21), 0.3 |
Normal weight | 13,505 | 2918 (21.6) | Ref | Ref | Ref | |
Overweight | 5506 | 1253 (22.8) | 1.05 (0.98, 1.12), 0.1 | 1.02 (0.96, 1.09), 0.5 | 1.03 (0.96, 1.09), 0.4 | |
Obese | 3288 | 868 (26.4) | 1.22 (1.14, 1.32), < 0.001 | 1.13 (1.05, 1.21), 0.001 | 1.14 (1.06, 1.23), < 0.001 | |
Smoking | Never smoker | 13,071 | 2749 (21.0) | Ref | Ref | Ref |
Former smoker | 5712 | 1326 (23.2) | 1.10 (1.03, 1.17), 0.003 | 0.99 (0.94, 1.06), 0.9 | 0.98 (0.92, 1.04), 0.5 | |
< 10 cigarettes per day | 1814 | 442 (24.4) | 1.16 (1.05, 1.28), 0.003 | 1.02 (0.93, 1.13), 0.6 | 1.00 (0.91, 1.10), 0.9 | |
10–19 cigarettes per day | 1404 | 397 (28.3) | 1.37 (1.24, 1.51), < 0.001 | 1.13 (1.02, 1.25), 0.02 | 1.09 (0.98, 1.21), 0.1 | |
20 or more cigarettes per day | 889 | 244 (27.4) | 1.34 (1.19, 1.51), < 0.001 | 1.07 (0.94, 1.21), 0.3 | 1.03 (0.91, 1.17), 0.6 | |
Unknown amount of smoking | 613 | 159 (25.9) | 1.30 (1.13, 1.50), < 0.001 | 1.06 (0.90, 1.25), 0.5 | 1.02 (0.86, 1.22), 0.8 | |
Alcohol intake | Low risk drinker | 19,957 | 4544 (22.8) | Ref | Ref | Ref |
Non-drinker | 2700 | 513 (19.0) | 0.81 (0.74, 0.89), < 0.001 | 0.82 (0.75, 0.89), < 0.001 | 0.81 (0.74, 0.89), < 0.001 | |
Risky drinker | 846 | 260 (30.7) | 1.36 (1.22, 1.52), < 0.001 | 1.15 (1.03, 1.28), 0.02 | 1.13 (1.01, 1.27), 0.04 |