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Table 5 Stratified analyses of potential modification effect for the impact of total cholesterol and egg intake on GDM

From: Dietary cholesterol and egg intake are associated with the risk of gestational diabetes: a prospective study from Southwest China

Stratification factors   Total cholesterol intake
(each additional 100 mg/d) a
Egg intake (each additional egg/d) a
N OR 95%CI P for interaction OR 95%CI P for interaction
All participants 1617 1.07 1.02-1.13 - 1.32 1.11-1.58 -
Age (years)
 <30 969 1.02 0.95-1.10 0.048 1.12 0.89-1.42 0.036
 ≥30 648 1.24 1.12-1.32   1.66 1.24-2.22  
Prepregnancy BMI (kg/m2)
 <24 1369 1.07 1.02-1.14 0.985 1.31 1.08-1.58 0.676
 ≥24 248 1.06 0.91-1.24   1.50 0.86-2.61  
Parity
 Primiparous 1157 1.06 1.00-1.13 0.575 1.28 1.03, 1.58 0.673
 Multiparous 460 1.11 1.0-1.22   1.46 1.04, 2.05  
Physical activity (MET-h wk-1)
 <Median 809 1.48 1.14-1.93 0.396 1.11 1.02, 1.20 0.262
 ≥Median 808 1.21 0.94-1.54   1.05 0.98, 1.13  
Family history of diabetes
 Yes 162 1.03 0.87-1.21 0.994 1.16 0.67, 2.00 0.964
 No 1455 1.07 1.02-1.13   1.32 1.09, 1.60  
Plasma TG (mmol/L)
 <Median 828 1.06 0.97-1.15 0.019 1.29 0.97-1.71 0.260
 ≥Median 789 1.10 1.01-1.19   1.33 1.04-1.70  
Plasma TC (mmol/L)
 <Median 894 1.03 0.95-1.11 0.006 1.19 0.93-1.53 0.011
 ≥Median 723 1.14 1.04-1.25   1.51 1.14-2.01  
Plasma LDL-C (mmol/L)
 <Median 893 1.02 0.95-1.09 0.022 1.10 0.86-1.40 0.023
 ≥Median 724 1.15 1.07-1.24   1.68 1.28-2.21  
Plasma HDL-C (mmol/L)
 <Median 808 1.02 0.94-1.10 0.119 1.17 0.90-1.52 0.241
 ≥Median 809 1.11 1.04-1.20   1.47 1.14-1.89  
  1. BMI body mass index, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GDM gestational diabetes mellitus, MET metabolic equivalent
  2. a Adjusted for energy intake, age, prepregnancy BMI, education, income of family, parity, family history of diabetes, smoking before pregnancy, alcohol consumption before pregnancy, physical activity, dietary glycemic load, weight gain from pregnancy to OGTT