Dietary cholesterol and egg intake are associated with the risk of gestational diabetes: a prospective study from Southwest China

Table 5 Stratified analyses of potential modification effect for the impact of total cholesterol and egg intake on GDM

Stratification factors		Total cholesterol intake (each additional 100 mg/d) ^a			Egg intake (each additional egg/d) ^a
Stratification factors	N	OR	95%CI	P for interaction	OR	95%CI	P for interaction
All participants	1617	1.07	1.02-1.13	-	1.32	1.11-1.58	-
Age (years)
<30	969	1.02	0.95-1.10	0.048	1.12	0.89-1.42	0.036
≥30	648	1.24	1.12-1.32		1.66	1.24-2.22
Prepregnancy BMI (kg/m²)
<24	1369	1.07	1.02-1.14	0.985	1.31	1.08-1.58	0.676
≥24	248	1.06	0.91-1.24		1.50	0.86-2.61
Parity
Primiparous	1157	1.06	1.00-1.13	0.575	1.28	1.03, 1.58	0.673
Multiparous	460	1.11	1.0-1.22		1.46	1.04, 2.05
Physical activity (MET^-h wk^-1)
<Median	809	1.48	1.14-1.93	0.396	1.11	1.02, 1.20	0.262
≥Median	808	1.21	0.94-1.54		1.05	0.98, 1.13
Family history of diabetes
Yes	162	1.03	0.87-1.21	0.994	1.16	0.67, 2.00	0.964
No	1455	1.07	1.02-1.13		1.32	1.09, 1.60
Plasma TG (mmol/L)
<Median	828	1.06	0.97-1.15	0.019	1.29	0.97-1.71	0.260
≥Median	789	1.10	1.01-1.19		1.33	1.04-1.70
Plasma TC (mmol/L)
<Median	894	1.03	0.95-1.11	0.006	1.19	0.93-1.53	0.011
≥Median	723	1.14	1.04-1.25		1.51	1.14-2.01
Plasma LDL-C (mmol/L)
<Median	893	1.02	0.95-1.09	0.022	1.10	0.86-1.40	0.023
≥Median	724	1.15	1.07-1.24		1.68	1.28-2.21
Plasma HDL-C (mmol/L)
<Median	808	1.02	0.94-1.10	0.119	1.17	0.90-1.52	0.241
≥Median	809	1.11	1.04-1.20		1.47	1.14-1.89

BMI body mass index, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, GDM gestational diabetes mellitus, MET metabolic equivalent
^a Adjusted for energy intake, age, prepregnancy BMI, education, income of family, parity, family history of diabetes, smoking before pregnancy, alcohol consumption before pregnancy, physical activity, dietary glycemic load, weight gain from pregnancy to OGTT

ISSN: 1471-2393