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Table 2 Summary and review of case reports in pregnant women with subacute thyroiditis

From: Subacute thyroiditis during early pregnancy: a case report and literature review

Case report time Age Time of SAT Symptoms Physical examination of thyroid gland Thyroid ultrasound Treatment Delivery time Newborn weight(g) Apgar score Postpartum thyroid function test results
Case 1 (year 2006) 35Y 11 W fever, tired, Neck pain enlarged thyroid gland and tender on plapation Irregular hypoechoic zone was find in thyroid gland with irregular edges Prednisone 20 mg per day, halved after 2 weeks; Liothyronine 10ug per day at 27 weeks of pregnancy, L-T4 50ug per day at 29 weeks until delivery 41 W 3968 10,10 Not provided
Case 2 (year 2006) 31 Y 6 W Neck pain enlarged right thyroid gland, firm and tender on plapation Irregular hypoechoic thyroid gland on the right, 41 days later, the ultrasound findings on the left are as same as those on the right Untreated 42 W 3265 9,10 Not provided
Case 3 (year 2010) 30 Y 6 W Neck pain, tired enlarged thyroid gland and tender on plapation Irregular hypoechoic zone was find in thyroid gland with irregular edges L-T4 50-75ug per day at 14 weeks of pregnancy 39 W 2720 9,10 Normal range
Case 4 (year 2012) 28 Y 9 W Neck pain, tired enlarged thyroid gland, firm and tender on plapation The border of the right thyroid gland is not clear and the texture is uneven L-T4 50ug per day at 20 weeks of gestation, 62.3ug per day after 3 weeks, and gradually reduce the dose to stop taking the drug after delivery 40 W 3400 10,10 Normal range
Case 5 (year 2012) 29 Y 5 W unbearable to heat, palpitations, Neck pain The right thyroid gland is enlarged slightly Decreased in blood flow Prednisone 1 mg/kg per day, stop taking prednisone after 2 months and oral L-T4 in dose of 2 µg/kg per day, increase to 2.4 µg/kg per day after 6 weeks, stop in 1 month postpartum Not provided Not provided Not provided Not provided
Case 6 (year 2015) 33 Y 13 W Neck pain and tumefaction, tired enlarged thyroid gland and tender on plapation Not provided Acetaminophen 3 × 500 mg per day, stop after 10 days and supplement L-T4 50ug per day, increase to 75ug per day after 3 weeks until delivery 38 W 3740 Not provided Normal range
Case 7 (year 2015) 29 Y 5 W Neck pain, tired, severe nausea and vomiting enlarged thyroid gland Abnormal thyroid texture Prednisone 20 mg per day, pregnancy was terminated due to severe nausea and vomiting at 11 weeks _ _ _ _
The case (year 2020) 27 Y 12 W Unbearable neck pain enlarged thyroid gland, firm and tender on plapation Reduced in thyroid echo and texture was uneven Topical hydrocortisone cream for neck, oral prednisone 10 mg per day after 2 days, increase to 15 mg per day after 10 days, stop at 27 weeks of gestation; L-T4 25ug per day at 25 weeks of gestation, increase to 50ug per day at 31 weeks of gestation to delivery 41 W 3600 9, 10 Normal range
  1. Y years old, W Weeks of gestation