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Table 2 Summary and review of case reports in pregnant women with subacute thyroiditis

From: Subacute thyroiditis during early pregnancy: a case report and literature review

Case report time

Age

Time of SAT

Symptoms

Physical examination of thyroid gland

Thyroid ultrasound

Treatment

Delivery time

Newborn weight(g)

Apgar score

Postpartum thyroid function test results

Case 1 (year 2006)

35Y

11 W

fever, tired, Neck pain

enlarged thyroid gland and tender on plapation

Irregular hypoechoic zone was find in thyroid gland with irregular edges

Prednisone 20 mg per day, halved after 2 weeks; Liothyronine 10ug per day at 27 weeks of pregnancy, L-T4 50ug per day at 29 weeks until delivery

41 W

3968

10,10

Not provided

Case 2 (year 2006)

31 Y

6 W

Neck pain

enlarged right thyroid gland, firm and tender on plapation

Irregular hypoechoic thyroid gland on the right, 41 days later, the ultrasound findings on the left are as same as those on the right

Untreated

42 W

3265

9,10

Not provided

Case 3 (year 2010)

30 Y

6 W

Neck pain, tired

enlarged thyroid gland and tender on plapation

Irregular hypoechoic zone was find in thyroid gland with irregular edges

L-T4 50-75ug per day at 14 weeks of pregnancy

39 W

2720

9,10

Normal range

Case 4 (year 2012)

28 Y

9 W

Neck pain, tired

enlarged thyroid gland, firm and tender on plapation

The border of the right thyroid gland is not clear and the texture is uneven

L-T4 50ug per day at 20 weeks of gestation, 62.3ug per day after 3 weeks, and gradually reduce the dose to stop taking the drug after delivery

40 W

3400

10,10

Normal range

Case 5 (year 2012)

29 Y

5 W

unbearable to heat, palpitations, Neck pain

The right thyroid gland is enlarged slightly

Decreased in blood flow

Prednisone 1 mg/kg per day, stop taking prednisone after 2 months and oral L-T4 in dose of 2 µg/kg per day, increase to 2.4 µg/kg per day after 6 weeks, stop in 1 month postpartum

Not provided

Not provided

Not provided

Not provided

Case 6 (year 2015)

33 Y

13 W

Neck pain and tumefaction, tired

enlarged thyroid gland and tender on plapation

Not provided

Acetaminophen 3 × 500 mg per day, stop after 10 days and supplement L-T4 50ug per day, increase to 75ug per day after 3 weeks until delivery

38 W

3740

Not provided

Normal range

Case 7 (year 2015)

29 Y

5 W

Neck pain, tired, severe nausea and vomiting

enlarged thyroid gland

Abnormal thyroid texture

Prednisone 20 mg per day, pregnancy was terminated due to severe nausea and vomiting at 11 weeks

_

_

_

_

The case (year 2020)

27 Y

12 W

Unbearable neck pain

enlarged thyroid gland, firm and tender on plapation

Reduced in thyroid echo and texture was uneven

Topical hydrocortisone cream for neck, oral prednisone 10 mg per day after 2 days, increase to 15 mg per day after 10 days, stop at 27 weeks of gestation; L-T4 25ug per day at 25 weeks of gestation, increase to 50ug per day at 31 weeks of gestation to delivery

41 W

3600

9, 10

Normal range

  1. Y years old, W Weeks of gestation