From: Subacute thyroiditis during early pregnancy: a case report and literature review
Case report time | Age | Time of SAT | Symptoms | Physical examination of thyroid gland | Thyroid ultrasound | Treatment | Delivery time | Newborn weight(g) | Apgar score | Postpartum thyroid function test results |
---|---|---|---|---|---|---|---|---|---|---|
Case 1 (year 2006) | 35Y | 11 W | fever, tired, Neck pain | enlarged thyroid gland and tender on plapation | Irregular hypoechoic zone was find in thyroid gland with irregular edges | Prednisone 20 mg per day, halved after 2 weeks; Liothyronine 10ug per day at 27 weeks of pregnancy, L-T4 50ug per day at 29 weeks until delivery | 41 W | 3968 | 10,10 | Not provided |
Case 2 (year 2006) | 31 Y | 6 W | Neck pain | enlarged right thyroid gland, firm and tender on plapation | Irregular hypoechoic thyroid gland on the right, 41 days later, the ultrasound findings on the left are as same as those on the right | Untreated | 42 W | 3265 | 9,10 | Not provided |
Case 3 (year 2010) | 30 Y | 6 W | Neck pain, tired | enlarged thyroid gland and tender on plapation | Irregular hypoechoic zone was find in thyroid gland with irregular edges | L-T4 50-75ug per day at 14 weeks of pregnancy | 39 W | 2720 | 9,10 | Normal range |
Case 4 (year 2012) | 28 Y | 9 W | Neck pain, tired | enlarged thyroid gland, firm and tender on plapation | The border of the right thyroid gland is not clear and the texture is uneven | L-T4 50ug per day at 20 weeks of gestation, 62.3ug per day after 3 weeks, and gradually reduce the dose to stop taking the drug after delivery | 40 W | 3400 | 10,10 | Normal range |
Case 5 (year 2012) | 29 Y | 5 W | unbearable to heat, palpitations, Neck pain | The right thyroid gland is enlarged slightly | Decreased in blood flow | Prednisone 1 mg/kg per day, stop taking prednisone after 2 months and oral L-T4 in dose of 2 µg/kg per day, increase to 2.4 µg/kg per day after 6 weeks, stop in 1 month postpartum | Not provided | Not provided | Not provided | Not provided |
Case 6 (year 2015) | 33 Y | 13 W | Neck pain and tumefaction, tired | enlarged thyroid gland and tender on plapation | Not provided | Acetaminophen 3 × 500 mg per day, stop after 10 days and supplement L-T4 50ug per day, increase to 75ug per day after 3 weeks until delivery | 38 W | 3740 | Not provided | Normal range |
Case 7 (year 2015) | 29 Y | 5 W | Neck pain, tired, severe nausea and vomiting | enlarged thyroid gland | Abnormal thyroid texture | Prednisone 20 mg per day, pregnancy was terminated due to severe nausea and vomiting at 11 weeks | _ | _ | _ | _ |
The case (year 2020) | 27 Y | 12 W | Unbearable neck pain | enlarged thyroid gland, firm and tender on plapation | Reduced in thyroid echo and texture was uneven | Topical hydrocortisone cream for neck, oral prednisone 10 mg per day after 2 days, increase to 15 mg per day after 10 days, stop at 27 weeks of gestation; L-T4 25ug per day at 25 weeks of gestation, increase to 50ug per day at 31 weeks of gestation to delivery | 41 W | 3600 | 9, 10 | Normal range |