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Table 4 Screening performance of the studied facial ultrasound markers for the fetuses with Down syndrome

From: Utility of fetal facial markers on a second trimester genetic sonogram in screening for Down syndrome in a high-risk Thai population

  PT NBL PT/NBL ratio NBL/ PT ratio
Sensitivity (%) 91 100 100 100
Specificity (%) 93 92 92 92
False positive (%) 6.76 7.6 6.5 7.6
False negative (%) 9.0 0 0 0
Positive predictive value 30 30 30 30
Negative predictive value 100 100 100 100
Positive likelihood ratio 13.44 13.08 13.08 13.08
Negative likelihood ratio 0.14 0.00 0.00 0.00
AUC 0.921 0.962 0.968 0.969
  1. AUC Area under the curve, PT Prenasal thickness, NBL Nasal bone length