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Table 5 Effect size of endometrial preparation on live birth rate in prespecified and exploratory subgroups in each subgroup

From: Pretreatment with a GnRH agonist and hormone replacement treatment protocol could not improve live birth rate for PCOS women undergoing frozen-thawed embryo transfer cycles

Characteristic

No. of participants

OR (95%CI) a

P-value

P for interaction

Endometrial thickness on the day of progesterone administration (mm)

   

0.952

  Tertile 1 (< 9.00)

531

1.11 (0.74, 1.67)

0.609

 

  Tertile 2 (9.00–10.30)

537

1.22 (0.85, 1.75)

0.292

 

  Tertile 3 (> 10.30)

570

1.16 (0.82, 1.64)

0.404

 

Triple-line endometrial pattern

 A

178

1.02 (0.56, 1.86)

0.956

0.169

 B

1344

1.19 (0.94, 1.50)

0.156

 

 C

116

2.34 (1.04, 5.29)

0.041

 

Number of transferred embryos

 1

431

0.94 (0.62, 1.41)

0.760

0.227

 2

1192

1.34 (1.05, 1.73)

0.021

 

 3

15

1.25 (0.16, 9.92)

0.833

 

Female age at embryo transfer

 Tertile 1 (< 27)

428

1.15 (0.74, 1.79)

0.529

0.311

 Tertile 2 (27–29)

591

1.00 (0.71, 1.42)

0.978

 

 Tertile 3 (> 29)

619

1.51 (1.08, 2.13)

0.017

 

Fertilization type

 IVF

1325

1.17 (0.92, 1.48)

0.200

0.257

 ICSI

253

1.25 (0.74, 2.12)

0.410

 

 IVF + ICSI

60

3.24 (1.04, 10.10)

0.043

 

Protocol in the fresh cycle

 Agonist

1489

1.22 (0.98, 1.53)

0.074

0.849

 Antagonist

145

1.02 (0.49, 2.11)

0.959

 

 Other

4

   
  1. χ2 test, Student’s t test
  2. a Adjusted for AFC, BMI, infertility duration, infertility type and cause of infertility except the subgroup variable