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Table 2 Baseline characteristics between different endometrial preparation groups

From: Pretreatment with a GnRH agonist and hormone replacement treatment protocol could not improve live birth rate for PCOS women undergoing frozen-thawed embryo transfer cycles

 

Matched Cohort (n = 1028) a

Entire Cohort (n = 1638) b

Variable

HRT (n = 514)

GnRHa+HRT (n = 514)

P-value

HRT (n = 1115)

GnRHa+HRT (n = 523)

P-value

Female age at oocyte retrieval (years)

28.53 ± 3.44

28.53 ± 3.16

0.698

28.16 ± 3.35

28.49 ± 3.17

0.059

Female age at embryo transfer (years)

28.96 ± 3.48

29.08 ± 3.18

0.330

28.61 ± 3.38

29.08 ± 3.16

0.007

Infertility duration (years)

3.59 ± 2.31

3.60 ± 2.12

0.500

3.59 ± 2.29

3.61 ± 2.13

0.896

BMI (kg/m2)

24.15 ± 3.60

24.15 ± 3.73

0.886

23.96 ± 3.49

24.12 ± 3.74

0.396

AFC (n)

22.22 ± 3.28

22.51 ± 3.33

0.197

22.30 ± 3.36

22.49 ± 3.35

0.285

Number of oocytes retrieved (n)

19.15 ± 8.41

17.71 ± 7.52

0.004

19.95 ± 8.30

17.65 ± 7.54

< 0.001

Fertilization type (n, %)

  

0.769

  

0.871

IVF

407 (79.18%)

413 (80.35%)

 

904 (81.08%)

421 (80.50%)

 

ICSI

88 (17.12%)

80 (15.56%)

 

172 (15.43%)

81 (15.49%)

 

IVF + ICSI

19 (3.70%)

21 (4.09%)

 

39 (3.50%)

21 (4.02%)

 

Infertility type (n, %)

  

0.690

  

0.647

Primary infertility

372 (72.66%)

367 (71.54%)

 

783 (70.35%)

373 (71.46%)

 

Secondary infertility

140 (27.34%)

146 (28.46%)

 

330 (29.65%)

149 (28.54%)

 

Cause of infertility (n, %)

  

0.431

  

0.371

Tubal

31 (6.04%)

20 (3.89%)

 

69 (6.19%)

22 (4.21%)

 

Ovulation disorder

185 (36.06%)

184 (35.80%)

 

388 (34.83%)

186 (35.56%)

 

Male factor

12 (2.34%)

11 (2.14%)

 

29 (2.60%)

11 (2.10%)

 

Mixed factor

285 (55.56%)

299 (58.17%)

 

628 (56.37%)

304 (58.13%)

 

Protocol in the fresh cycle (n, %)

  

0.159

  

0.477

Agonist

460 (89.49%)

474 (92.22%)

 

1007 (90.31%)

482 (92.16%)

 

Antagonist

53 (10.31%)

40 (7.78%)

 

105 (9.42%)

40 (7.65%)

 

Other

1 (0.19%)

0 (0.00%)

 

3 (0.27%)

1 (0.19%)

 

Gonadotropin dosage (IU)

2081.08 ± 924.44

2152.95 ± 965.73

0.223

2001.76 ± 891.03

2135.55 ± 979.92

0.006

Gonadotropin duration (days)

11.23 ± 3.18

12.73 ± 8.29

< 0.001

10.89 ± 3.12

12.62 ± 8.31

< 0.001

  1. χ2 test, Student’s t test
  2. a Propensity score-matched cohort, b before propensity score matching