Matched Cohort (n = 1028) a | Entire Cohort (n = 1638) b | |||||
---|---|---|---|---|---|---|
Variable | HRT (n = 514) | GnRHa+HRT (n = 514) | P-value¶ | HRT (n = 1115) | GnRHa+HRT (n = 523) | P-value¶ |
Female age at oocyte retrieval (years) | 28.53 ± 3.44 | 28.53 ± 3.16 | 0.698 | 28.16 ± 3.35 | 28.49 ± 3.17 | 0.059 |
Female age at embryo transfer (years) | 28.96 ± 3.48 | 29.08 ± 3.18 | 0.330 | 28.61 ± 3.38 | 29.08 ± 3.16 | 0.007 |
Infertility duration (years) | 3.59 ± 2.31 | 3.60 ± 2.12 | 0.500 | 3.59 ± 2.29 | 3.61 ± 2.13 | 0.896 |
BMI (kg/m2) | 24.15 ± 3.60 | 24.15 ± 3.73 | 0.886 | 23.96 ± 3.49 | 24.12 ± 3.74 | 0.396 |
AFC (n) | 22.22 ± 3.28 | 22.51 ± 3.33 | 0.197 | 22.30 ± 3.36 | 22.49 ± 3.35 | 0.285 |
Number of oocytes retrieved (n) | 19.15 ± 8.41 | 17.71 ± 7.52 | 0.004 | 19.95 ± 8.30 | 17.65 ± 7.54 | < 0.001 |
Fertilization type (n, %) | 0.769‡ | 0.871‡ | ||||
IVF | 407 (79.18%) | 413 (80.35%) | 904 (81.08%) | 421 (80.50%) | ||
ICSI | 88 (17.12%) | 80 (15.56%) | 172 (15.43%) | 81 (15.49%) | ||
IVF + ICSI | 19 (3.70%) | 21 (4.09%) | 39 (3.50%) | 21 (4.02%) | ||
Infertility type (n, %) | 0.690‡ | 0.647‡ | ||||
Primary infertility | 372 (72.66%) | 367 (71.54%) | 783 (70.35%) | 373 (71.46%) | ||
Secondary infertility | 140 (27.34%) | 146 (28.46%) | 330 (29.65%) | 149 (28.54%) | ||
Cause of infertility (n, %) | 0.431‡ | 0.371‡ | ||||
Tubal | 31 (6.04%) | 20 (3.89%) | 69 (6.19%) | 22 (4.21%) | ||
Ovulation disorder | 185 (36.06%) | 184 (35.80%) | 388 (34.83%) | 186 (35.56%) | ||
Male factor | 12 (2.34%) | 11 (2.14%) | 29 (2.60%) | 11 (2.10%) | ||
Mixed factor | 285 (55.56%) | 299 (58.17%) | 628 (56.37%) | 304 (58.13%) | ||
Protocol in the fresh cycle (n, %) | 0.159‡ | 0.477‡ | ||||
Agonist | 460 (89.49%) | 474 (92.22%) | 1007 (90.31%) | 482 (92.16%) | ||
Antagonist | 53 (10.31%) | 40 (7.78%) | 105 (9.42%) | 40 (7.65%) | ||
Other | 1 (0.19%) | 0 (0.00%) | 3 (0.27%) | 1 (0.19%) | ||
Gonadotropin dosage (IU) | 2081.08 ± 924.44 | 2152.95 ± 965.73 | 0.223 | 2001.76 ± 891.03 | 2135.55 ± 979.92 | 0.006 |
Gonadotropin duration (days) | 11.23 ± 3.18 | 12.73 ± 8.29 | < 0.001 | 10.89 ± 3.12 | 12.62 ± 8.31 | < 0.001 |