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Table 3 Associations between parental prepregnancy BMI and neonatal outcomes of singletons in multilevel logistic regression analyses

From: Association of parental prepregnancy BMI with neonatal outcomes and birth defect in fresh embryo transfer cycles: a retrospective cohort study

Variable

IVF

ICSI

A(M&P < 25)

B(M < 25&P ≥ 25)

C(M ≥ 25&P < 25)

D(M&P ≥ 25)

A(M&P < 25)

B(M < 25&P ≥ 25)

C(M ≥ 25&P < 25)

D(M&P ≥ 25)

Cesarean section

401(60.0)

179(60.1)

71(76.3)

40(66.7)

128(54.7)

73(62.4)

31(73.8)

13(59.1)

 aOR (95% CI) a

REF

0.96(0.72,1.27)

1.98(1.19,3.30)

1.30(0.73,2.29)

REF

1.37(0.87,2.18)

2.52(1.18,5.36)

1.25(0.51,3.08)

 P value b

 

0.755

0.008

0.374

 

0.177

0.017

0.633

Gender(Boys)

375(56.1)

162(54.4)

36(38.7)

27(45.0)

120(51.3)

61(52.1)

24(57.1)

7(31.8)

 aOR (95% CI) a

REF

0.93(0.71,1.23)

0.49(0.31,0.77)

0.65(0.38,1.11)

REF

1.02(0.65,1.60)

1.28(0.65,2.51)

0.44(0.17,1.13)

 P value b

 

0.617

0.002

0.113

 

0.923

0.477

0.088

Low birth weight infant

35(5.2)

15(5.0)

11(11.8)

2(3.3)

10(4.3)

5(4.3)

3(7.1)

0

 aOR (95% CI) a

REF

0.97(0.52,1.81)

2.42(1.16,5.02)

0.60(0.14,2.61)

REF

1.08(0.35,3.30)

2.10(0.52,8.54)

–

 P value b

 

0.924

0.018

0.499

 

0.897

0.298

–

Fetal macrosomia

34(5.1)

16(5.4)

7(7.5)

9(15.0)

18(7.7)

9(7.7)

8(19.0)

3(13.6)

 aOR (95% CI) a

REF

1.05(0.57,1.95)

1.48(0.63,3.48)

3.20(1.43,7.18)

REF

1.10(0.47,2.56)

3.48(1.32,9.19)

1.81(0.47,6.92)

 P value b

 

0.866

0.369

0.005

 

0.832

0.012

0.386

LGA

68(10.2)

48(16.1)

20(21.5)

12(20.0)

29(12.4)

14(12.0)

11(26.2)

7(31.8)

 aOR (95% CI) a

REF

1.70(1.14,2.54)

2.48(1.41,4.36)

2.27(1.14,4.52)

REF

1.04(0.52,2.08)

2.94(1.27,6.81)

3.16(1.14,8.76)

 P value b

 

0.009

0.002

0.020

 

0.913

0.012

0.027

  1. Values are presented as frequency (percentage)
  2. a aOR: Odds ratio and 95% confidence interval (CI) were calculated from logistic regression models to reflect the associations between parental prepregnancy BMI and neonatal outcomes of singletons. Adjusted models are controlled for parental age, type of infertility, duration of infertility, ovulatory dysfunction and endometriosis
  3. b P value is based on multilevel logistic regression analyses. Results in bold indicate statistical significance (P < 0.05)
  4. BMI body mass index, M maternal prepregnancy BMI, P paternal prepregnancy BMI, IVF in vitro fertilization, ICSI intracytoplasmic sperm injection, LGA large for gestational age, REF reference group
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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