| Normal Outcome (n = 420) (N(%)) | Adverse Outcome (n = 108) (N(%)) | Unadjusted | Model 1 | Model 2 | |||
---|---|---|---|---|---|---|---|---|
OR (95% CI) | P value | AOR (95% CI) | P value | AOR | P value | |||
Ethnicity | ||||||||
 European | 373 (89) | 101 (94) | Reference |  | Reference |  | Reference |  |
 Asian | 24 (6) | 5 (5) | 0.77 (0.29–2.07) | 0.49 | 0.73 (0.25–2.13) | 0.57 | 0.58 (0.18–1.88) | 0.37 |
 Other | 23 (5) | 2 (2) | 0.32 (0.74–1.38) | 0.08 | 0.27 (0.06–1.28) | 0.081 | 0.27 (0.54–1.32) | 0.11 |
Parity | ||||||||
 Nulliparous | 143 (34) | 47 (44) | Reference |  | Reference |  | Reference |  |
 Multiparous | 277 (66) | 61 (56) | 0.67 (0.44–1.03) | 0.07 | 0.58 (0.36–0.93) | 0.03 | 0.56 (0.33–0.89) | 0.02 |
ART | ||||||||
 None | 383 (91) | 99 (92) | Reference |  | Reference |  | Reference |  |
 ART | 37 (9) | 9 (8) | 0.94 (0.44–2.01) | 0.88 | 1.01 (0.44–2.29) | 0.99 | 0.85 (0.35–2.04) | 0.71 |
Smoking | ||||||||
 No | 332 (79) | 66 (61) | Reference |  | Reference |  | Reference |  |
 Ex | 69 (16) | 27 (25) | 1.96 (1.17–3.30) | 0.01 | 1.86 (1.08–3.24) | 0.03 | 1.85 (1.05–3.25) | 0.03 |
 Current | 19 (5) | 15 (14) | 3.97 (1.92–8.21) | < 0.001 | 4.24 (1.88–9.54) | < 0.001 | 4.22 (1.83–9.75) | 0.001 |
Housing | ||||||||
 Rented | 123 (29) | 45 (42) | Reference |  | Reference |  | Reference |  |
 Owns | 297 (71) | 63 (58) | 0.58 (0.37–0.90) | 0.01 | 0.57 (0.34–0.97) | 0.04 | 0.56 (0.32–0.98) | 0.04 |
IMD Quintile | ||||||||
 1st | 73 (18) | 19 (18) | Reference |  | Reference |  | Reference |  |
 2nd | 78 (20) | 29 (27) | 1.42 (0.74–2.74) | 0.29 | 1.31 (0.66–2.60) | 0.53 | 1.37 (0.68–2.76) | 0.38 |
 3rd | 97 (24) | 13 (12) | 0.51 (0.24–1.11) | 0.09 | 0.46 (0.21–101) | 0.05 | 0.48 (0.21–1.10) | 0.08 |
 4th | 68 (17) | 21 (20) | 1.19 (0.59–2.40) | 0.63 | 0.92 (0.44–1.93) | 0.82 | 0.98 (0.46–2.10) | 0.97 |
 5th | 82 (21) 22 missing values | 14 (23) 2 missing values | 1.12 (0.57–2.22) | 0.74 | 0.98 (0.46–2.08) | 0.96 | 1.02 (0.48–2.23) | 0.94 |
Paternal Age | ||||||||
 < 30 years | 86 (21) | 33 (32) | Reference |  |  |  | Reference |  |
 30–34 years | 58 (14) | 16 (15) | 0.77 (0.39–1.51) | 0.45 |  |  | 0.86 | 0.72 |
 35–39 years | 115 (28) | 24 (23) | 0.54 (0.30–0.98) | 0.04 |  |  | 0.54 | 0.16 |
 ≥40 years | 148 (36) 13 missing values | 31 (90) 4 missing values | 0.54 (0.31–0.94) | 0.03 |  |  | 0.46 | 0.08 |