Effect of low-molecular-weight heparins on anti-Xa peak levels and adverse reactions in Chinese patients with recurrent spontaneous abortion: a single-center, observational study

Table 4 Impact of LMWHs on coagulation status

TEG Parameters	Nadroparin group (n = 152)	Enoxaparin group (n = 113)	Dalteparin group (n = 45)	P value
R time	8.09 ± 2.28	8.60 ± 2.42	9.40 ± 3.48	0.06
K time	1.64 ± 0.53	1.76 ± 0.58	2.08 ± 0.95	0.003^b
Angle α	71.17 ± 5.03	70.26 ± 5.52	66.84 ± 8.53	0.002^b; 0.04^,c
MA	63.53 ± 4.52	63.25 ± 4.77	61.83 ± 4.71	0.11
CI	−0.51 ± 2.09	−0.98 ± 2.33	−2.06 ± 3.38	0.02^b

Results were presented as mean ± SD
Normal range of R time, K time, angle α, MA and CI is 5–10 min, 1–3 min, 53–72°, 50–70 mm and − 3-3, respectively
R time reaction time, K time clot formation time, Angle α angle degree, MA maximum amplitude, CI coagulation index, SD standard deviation
^b Nadroparin group vs. dalteparin group
^c Enoxaparin group vs. dalteparin group

ISSN: 1471-2393