Skip to main content

Table 2 The association between maternal life events and CHD in offspring

From: Maternal exposure to life events during pregnancy and congenital heart disease in offspring: a case-control study in a Chinese population

Life events Case group Control group OR (95%CI) a
(n = 699) (n = 1581) Unadjusted Adjusted
Continuous variables, \(\overline{x}\pm s\)
 Positive events 0.30±0.63 0.58±0.79 0.46 (0.40, 0.54) ** 0.52 (0.43, 0.62) **
 Negative events 1.12±2.06 0.72±1.46 1.26 (1.19, 1.34) ** 1.20 (1.12, 1.28) **
Categorical variables, n (%)
 Positive events
  No 539 (77.11) 889 (56.23) 1.00 1.00
  Yes 160 (22.89) 692 (43.77) 0.34 (0.28, 0.42) ** 0.38 (0.30, 0.48) **
 Negative events
  No 402 (57.51) 1029 (65.09) 1.00 1.00
  Yes 297 (42.49) 552 (34.91) 1.70 (1.40, 2.06) ** 1.62 (1.29, 2.03) **
  1. aLogistic model was used for estimating risk of life events with or without adjusting for covariates. Adjusted covariates included maternal age, residence, maternal education, paternal education, family history of CHD, history of parturition, history of abortion, infection during periconception, and abnormal prenatal examination
  2. * p < 0.01; ** p < 0.001