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Table 2 The association between maternal life events and CHD in offspring

From: Maternal exposure to life events during pregnancy and congenital heart disease in offspring: a case-control study in a Chinese population

Life events

Case group

Control group

OR (95%CI) a

(n = 699)

(n = 1581)

Unadjusted

Adjusted

Continuous variables, \(\overline{x}\pm s\)

 Positive events

0.30±0.63

0.58±0.79

0.46 (0.40, 0.54) **

0.52 (0.43, 0.62) **

 Negative events

1.12±2.06

0.72±1.46

1.26 (1.19, 1.34) **

1.20 (1.12, 1.28) **

Categorical variables, n (%)

 Positive events

  No

539 (77.11)

889 (56.23)

1.00

1.00

  Yes

160 (22.89)

692 (43.77)

0.34 (0.28, 0.42) **

0.38 (0.30, 0.48) **

 Negative events

  No

402 (57.51)

1029 (65.09)

1.00

1.00

  Yes

297 (42.49)

552 (34.91)

1.70 (1.40, 2.06) **

1.62 (1.29, 2.03) **

  1. aLogistic model was used for estimating risk of life events with or without adjusting for covariates. Adjusted covariates included maternal age, residence, maternal education, paternal education, family history of CHD, history of parturition, history of abortion, infection during periconception, and abnormal prenatal examination
  2. * p < 0.01; ** p < 0.001