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Table 1 Patient and pregnancy characteristics by transfusion volume

From: Place of birth and outcomes associated with large volume transfusion: an observational study

  

Total

N (Col %)

No transfusion

N (Col %)

1-3 Units

N (Col %)

4 or more units

N (Col %)

p-value*

 

N (Row %)

231603 (100.0)

227294 (98.1)

3298 (1.4)

1011 (0.4)

 

Hospital level

1-3

20070 ( 8.7)

19594 ( 8.6)

354 ( 10.7)

122 ( 12.1)

<.001

4-5

97022 ( 41.9)

95285 ( 41.9)

1372 ( 41.6)

365 ( 36.1)

 

Tertiary

114511 ( 49.4)

112415 ( 49.5)

1572 ( 47.7)

524 ( 51.8)

 

Total non-tertiary

117092 ( 50.6)

114879 ( 50.5)

1726 ( 52.3)

487 ( 48.2)

 

Hospital location

Urban

193665 ( 83.6)

190225 ( 83.7)

2626 ( 79.6)

814 ( 80.5)

<.001

Regional

37938 ( 16.4)

37069 ( 16.3)

672 ( 20.4)

197 ( 19.5)

 

Birth volume

<500

7873 ( 3.4)

7572 ( 3.3)

237 ( 7.2)

64 ( 6.3)

<.001

500-999

13800 ( 6.0)

13527 ( 6.0)

197 ( 6.0)

76 ( 7.5)

 

1000+

209930 ( 90.6)

206195 ( 90.7)

2864 ( 86.8)

871 ( 86.2)

 

Maternal age

<20 years

9290 ( 4.0)

9044 ( 4.0)

200 ( 6.1)

46 ( 4.5)

<.001

20-24

37999 ( 16.4)

37274 ( 16.4)

593 ( 18.0)

132 ( 13.1)

 

25-29

67242 ( 29.0)

66075 ( 29.1)

911 ( 27.6)

256 ( 25.3)

 

30-34

68556 ( 29.6)

67341 ( 29.6)

936 ( 28.4)

279 ( 27.6)

 

35+

48516 ( 20.9)

47560 ( 20.9)

658 ( 20.0)

298 ( 29.5)

 

Maternal country of birth

Australia/NZ

147844 ( 63.8)

145071 ( 63.8)

2141 ( 64.9)

632 ( 62.5)

<.001

NE/SE/South Asia

41967 ( 18.1)

41077 ( 18.1)

673 ( 20.4)

217 ( 21.5)

 

Other

40923 ( 17.7)

40288 ( 17.7)

476 ( 14.4)

159 ( 15.7)

 

Smoking during pregnancy

 

33013 ( 14.3)

32346 ( 14.2)

497 ( 15.1)

170 ( 16.8)

0.03

Previous uterine surgery (5 years)

 

376 ( 0.2)

359 ( 0.2)

9 ( 0.3)

8 ( 0.8)

<.001

Uterine fibroids (1 year)

 

313 ( 0.1)

297 ( 0.1)

9 ( 0.3)

7 ( 0.7)

<.001

Pre-existing diabetes

 

1567 ( 0.7)

1532 ( 0.7)

21 ( 0.6)

14 ( 1.4)

0.02

Chronic hypertension

 

2121 ( 0.9)

2065 ( 0.9)

42 ( 1.3)

14 ( 1.4)

0.03

Chronic Conditions

 

3695 ( 1.6)

3517 ( 1.5)

115 ( 3.5)

63 ( 6.2)

<.001

Previous CS

 

30065 ( 13.0)

29436 ( 13.0)

433 ( 13.1)

196 ( 19.4)

<.001

Parity

Primiparous

98589 ( 42.6)

96394 ( 42.4)

1750 ( 53.1)

445 ( 44.0)

<.001

1-4 previous births

130740 ( 56.5)

128691 ( 56.6)

1508 ( 45.7)

541 ( 53.5)

 

5+

2274 ( 1.0)

2209 ( 1.0)

40 ( 1.2)

25 ( 2.5)

 

Previous PPH

 

18013 ( 7.8)

16287 ( 7.2)

1283 ( 38.9)

443 ( 43.8)

<.001

Multiple pregnancy

 

3957 ( 1.7)

3766 ( 1.7)

142 ( 4.3)

49 ( 4.8)

<.001

Assisted Reproductive Technology

 

3484 ( 1.5)

3365 ( 1.5)

77 ( 2.3)

42 ( 4.2)

<.001

Placenta Praevia

 

2059 ( 0.9)

1746 ( 0.8)

189 ( 5.7)

124 ( 12.3)

<.001

Morbidly Adherent Placenta

 

442 ( 0.2)

228 ( 0.1)

109 ( 3.3)

105 ( 10.4)

<.001

Pregnancy Hypertension

 

16993 ( 7.3)

16384 ( 7.2)

471 ( 14.3)

138 ( 13.6)

<.001

Gestational Diabetes

 

16641 ( 7.2)

16319 ( 7.2)

241 ( 7.3)

81 ( 8.0)

0.57

Cephalic presentation

 

221431 ( 95.6)

217373 ( 95.6)

3124 ( 94.7)

934 ( 92.4)

<.001

Induction

 

60482 ( 26.1)

58998 ( 26.0)

1164 ( 35.3)

320 ( 31.7)

<.001

Pre-labour Caesarean

 

33755 ( 14.6)

32988 ( 14.5)

511 ( 15.5)

256 ( 25.3)

<.001

Abruption

 

1029 ( 0.4)

857 ( 0.4)

111 ( 3.4)

61 ( 6.0)

<.001

Gestational age

20-32

5354 ( 2.3)

5084 ( 2.2)

191 ( 5.8)

79 ( 7.8)

<.001

33-36

12653 ( 5.5)

12257 ( 5.4)

258 ( 7.8)

138 ( 13.6)

 

37+

213555 ( 92.2)

209912 ( 92.4)

2849 ( 86.4)

794 ( 78.5)

 

Large for gestational age (>90th centile)

 

24187 ( 10.4)

23526 ( 10.4)

521 ( 15.8)

140 ( 13.8)

<.001

  1. * chi-square test of difference in number of units transfused across levels of patient characteristics