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Table 3 Different types of vaginal microbiota diversity clusters in pregnant women in the sub-Saharan African region

From: Composition of the vaginal microbiota during pregnancy in women living in sub-Saharan Africa: a PRISMA-compliant review

Included articles that used VMB clustering Price et al. Gudza et al. Brabin et al. Borgdorff et al. Gautam et al. Frank et al. Donders et al.
Name of cluster Community state type (CST) ClusterR Cluster KRST Genus-level clustering morpho-types grades
Diversity group: Higher proportions of strictly anaerobic bacteria, including Prevotella, Dialister, Atopobium, Gardnerella, Megasphaera, Peptoniphilus, Sneathia, Eggerthella, Aerococcus, Finegoldia, and Mobiluncus. CST-IV       
Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1 and the presence of a lower abundance of L. iners.     R-III KRST-III   
Diversity group: Higher proportions of strictly anaerobic bacteria, especially G vaginalis, BVAB1.   CST-IVA      
Diversity group: Higher proportions of strictly anaerobic bacteria, especially G vaginalis, L iners, and A vaginae.   CST-IVB      
Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1, L. iners, and high abundance Gardnerella genus. CST-IV-I    R-IV KRST-IV   
Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1, and lower total bacterial abundance than the other mixed anaerobic clusters.     R-V KRST-V   
Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1, L. iners, and highest levels of Prevotella species.     R-VI KRST-VI   
Diversity group: Higher proportions of strictly anaerobic bacteria and G. vaginalis, and A. vaginae. CST-IV-II       
Diversity group: Higher proportions of strictly anaerobic bacteria other than G. vaginalis and A. vaginae. CST-IV-III       
Diversity group: pooled dysbiotic clusters.      KRST-pIII-V   
Diversity group: Mixed of variety of genera, dominated by Gardnerella spp. and Lactobacillus spp.       Cluster 3  
Diversity group: low Lactobacillus spp. and diverse anaerobic groups (eg, Prevotella, Sneathia, Peptostreptococcus)       Cluster 4  
Diversity group: lesser Lactobacillus spp mixed with other bacteria.        Grade II
Diversity group: Absence of Lactobacillus spp or overwhelming presence of other bacteria (not specified).    CST IV     Grade III
Diversity group: Dominated by coagulase-negative staphylococci (S. haemolyticus and S. epidermidis) with lesser quantities of lactobacilli       Cluster 2  
  1. CST community state types numeric system described by Ravel et al., [2]. R-clusters, vaginal microbiota cluster method in Rwandese women as described in Borgdorff et al. [36]. KRST-clusters, vaginal microbiota cluster method in Kenyan, Rwandese, South African and Tanzanian women as describe in Gautam et al. [8]