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Table 3 Association between mother's place of birth and Down syndrome screening (years: 2010+2016)

From: Does women’s place of birth affect their opportunity for an informed choice about Down syndrome screening? A population-based study in France

 

France

n=20 612

aOR(95% CI)a

Europe

n=861

aOR (95% CI)a

North Africa

n=1550

aOR (95% CI)a

Sub-Saharan Africa

n=960

aOR (95% CI)a

Other countries

n=661

aOR (95% CI)a

p

Did you have fetal nuchal translucency measured at your first-trimester ultrasound to learn your risk of Down syndrome?

No

1

1.55 (1.16-2.09)

3.94 (3.30-4.70)

2.58 (2.05-3.24)

3.10 (2.32-4.15)

 

Yes

1

1

1

1

1

 

I don't know

1

3.36 (2.73-4.13)

5.67 (4.88-6.59)

5.02 (4.20-6.00)

5.57 (4.43-6.99)

 
      

<0.001

Did you have a blood test to learn your risk for Down syndrome?

No

1

1.67 (1.36-2.05)

3.57 (3.13-4.08)

1.91 (1.60-2.29)

1.31 (1.01-1.70)

 

Yes

1

1

1

1

1

 

I don't know

1

5.24 (3.81-7.21)

8.30 (6.49-10.62)

6.65 (5.04-8.78)

9.14 (6.58-12.68)

 
      

<0.001

Opportunity to make an informed choice b

All women

1

2.27 (1.80-2.86)

3.84 (3.28-4.49)

3.27 (2.71-3.94)

3.28 (2.55-4.23)

 
      

<0.001

Women who had adequate prenatal care c

      
 

1

2.42 (1.85-3.15)

3.96 (3.31-4.75)

3.20 (2.55-4.00)

3.75 (2.84-4.96)

 
      

<0.001

  1. a Odds ratio adjusted for survey year, parity, age, mother's educational level and maternity ward level with confidence interval
  2. bAnswer "yes" if the serum marker assay was performed or refused, or if amniocentesis or a chorionic villus sampling was performed first. Answer "no" if the answer to the question "did you have a blood test to learn your risk of Down syndrome (serum markers)?" was "I don't know" or if the assay was not performed for one of the following reasons: not offered, because of late prenatal care, for another reason, or for an unknown reason (see Fig. 1)
  3. cat least 8 prenatal visits and 3 ultrasounds