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Table 1 The pre-pregnancy and pregnancy characteristics of participants stratified by the number of pregnancies

From: Women with multiple gestations have an increased risk of development of hypertension in the future

  Singleton
(n = 357,877)
Multiple gestations
(n = 4,944)
P-value
Age (years) 29.95 ± 3.27 30.02 ± 3.38  < 0.01
Advanced maternal age (%) 30,899 (8.63) 685 (13.86)  < 0.01
Primiparity (%) 214,451 (59.92) 3,893 (78.74)  < 0.01
Preeclampsia (%) 5919 (1.65) 374 (7.56)  < 0.01
Atrial fibrillation (%) 176 (0.05) 3 (0.06) 0.72
Regular exercise (%) 27,520 (7.69) 420 (8.50) 0.04
Smoker (%) 9,859 (2.75) 108 (2.18) 0.01
BMI (kg/m2) 20.75 ± 5.81 20.85 ± 2.71 0.23
Obesity (%) 23,335 (6.52) 371 (7.50)  < 0.01
Systolic BP (mmHg) 110.4 ± 10.54 110.6 ± 10.77 0.08
Diastolic BP (mmHg) 69.52 ± 7.86 69.60 ± 7.94 0.50
Fasting glucose (mg/dL) 85.93 ± 14.42 86.34 ± 12.87 0.04
DM (%) 3,324 (0.93) 71 (1.44)  < 0.01
TC (mg/dL) 174.0 ± 34.56 175.1 ± 35.20 0.03
High TC (%) 63,302 (17.69) 923 (18.67) 0.07
AST (mg/dL) 19.53 ± 11.38 19.89 ± 10.70 0.03
ALT (mg/dL) 15.41 ± 15.48 15.81 ± 14.27 0.07
Abnormal LFT (%) 13,531 (3.78) 205 (4.15) 0.18
  1. Regular exercise was defined as moderate-intensity exercise performed at least 3 d/wk
  2. Obesity by BMI; BMI ≥ 25 kg/m2, DM; fasting glucose ≥ 126 mg/dL at the NHSE or a medical claim for DM as a primary or secondary diagnosis before pregnancy based on ICD-10 codes, high TC; TC ≥ 200 mg/Dl, abnormal LFT; AST ≥ 31 or ALT ≥ 31 mg/dL
  3. Values are expressed as mean (SD) or n(%)
  4. BMI body mass index, BP blood pressure, DM diabetes mellitus, TC total cholesterol, AST aspartate aminotransferase, ALT alanine aminotransferase, LFT liver function test