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Table 3 Association of adverse pregnancy outcome among gestational diabetes mellitus with IOM guideline on total GWG

From: Association between gestational weight gain in women with gestational diabetes mellitus and adverse pregnancy outcomes: a retrospective cohort study

 

Within (n = 560)

Below (n = 545)

Above (n = 501)

n(%) (Reference)

n (%)

crude OR (95% CI)

Adjusted OR (95% CI)

n (%)

Crude OR (95% CI)

Adjusted OR (95% CI)

Caesarean delivery

235(42.0)

199(36.5)

0.80(0.62–1.01)

0.79(0.61–1.01)

247(49.3)

1.35(1.06–1.71)a

1.34(1.04–1.72)b

HDP

36(6.4)

25(4.6)

0.70(0.41–1.18)

0.63(0.406–1.11)

65(13.0)

2.17(1.15–3.32)b

2.00(1.28–3.12)b

preeclampsia

15(2.7)

11(2.0)

0.80(0.35–1.85)

0.83(0.35–1.97)

33(6.6)

2.30(1.17–4.53)b

2.06(1.01–4.21)b

PROM

263(47.0)

278(51.0)

1.18(0.93–1.49)

1.17(0.92–1.48)

147(29.3)

0.47(0.36–0.61)a

0.46(0.36–0.60)b

Postpartum hemorrhage

50(8.9)

58(10.6)

1.22(0.82–1.81)

1.24(0.83–1.85)

43(8.6)

0.96(0.63–1.47)

0.90(0.58–1.40)

Fetal distress

164(29.3)

152(27.9)

0.93(0.72–1.21)

0.93(0.72–1.22)

138(27.5)

0.92(0.71–1.20)

0.94(0.71–1.23)

Preterm birth

89(15.9)

138(25.3)

2.39(1.63–2.42)a

1.96(1.44–2.38)a

34(6.8)

0.39(0.25–0.58)a

0.35(0.23–0.44)a

Macrosomia

90(16.1)

33(6.1)

0.34(0.22–0.55)a

0.35(0.23–0.53)a

123(24.6)

1.70(1.25–2.30)a

1.55(1.13–2.13)b

SGA

41(7.3)

59(10.8)

1.43(1.23–1.69)a

1.32(1.11–1.50)b

21(4.2)

0.66(0.51–0.87)b

0.89(0.69–1.09)

LGA

126(22.5)

73(13.4)

0.47(0.35–0.68)a

0.54(0.42–0.72)a

183(36.5)

3.04(2.12–4.25)a

2.82(1.94–3.23)a

  1. Multivariate analyses were adjusted for maternal age, pre-pregnancy BMI, maternal education, IVF, FPG, 2-h blood glucose. The results were presented with an adjusted odds ratio, aOR (95% CI);
  2. IOM, Institute of Medicine; GWG, gestational weight gain; HDP, hypertensive disorders of pregnancy; PROM, premature rupture of the membranes; SGA, small for gestational age; LGA, large for gestational age; OR odds ratio; CI, Confidence interval
  3. aP < 0.01
  4. bP < 0.05,compared with the within IOM guideline subjects