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Table 2 Frequency and severity of adverse drugs observed during MDR/RR-TB treatment

From: Treatment and pregnancy outcomes of pregnant women exposed to second-line anti-tuberculosis drugs in South Africa

 

Total

(n = 35)

HIV Negative (n = 11)

HIV Positive

(n = 24)

p-value*

N (%)

N (%)

N (%)

 

Adverse events

No adverse events

18 (51.4)

9 (81.8)

9 (37.5)

0.027

Adverse events

17 (48.6)

2 (18.2)

15 (62.5)

 

1 event

14 (82.4)

2 (18.2)

12 (50.0)

 

 ≥ 2 events

3 (17.6)

-

3 (12.5)

 

TB regimen change

No

14 (40.0)

5 (45.5)

9 (37.5)

0.656

Yes

21 (60.0)

6 (54.5)

15 (62.5)

 
  1. TB Tuberculosis
  2. P values from Chi-square or Fisher’s exact tests. Chi-squared, P < 0.05- statistically significant