Skip to main content

Table 2  Multivariable regression of factors associated with Respiratory Distress Syndrome development

From: Do maternal demographics and prenatal history impact the efficacy of betamethasone therapy for threatened preterm labor?

  Adjusted Odds Ratios (CI)a  
Overall Cohort <14 Daysb <7 Days 2-7days Only 1 course
N 209 101 83 27 171
Maternal Age 1.01 (1.00-1.02) 1.01 (0.99-1.02) 1.01 (1.00-1.02) 1.01 (0.98-1.04) 1.00 (0.99-1.01)
Maternal BMIc at Dosing 1.00 (0.99-1.01) 1.00 (0.99-1.01) 1.00 (0.99-1.01) 1.00 (0.98-1.02) 1.00 (0.99-1.01)
Maternal Ethnicity, Hispanic 1.08 (0.95-1.22) 1.09 (0.89-1.32) 1.09 (0.88-1.35) 1.06 (0.71-1.57) 1.03 (0.91-1.17)
Maternal Race
 White or Caucasian Reference Reference Reference Reference Reference
 Black or African American 0.99 (0.90-1.09) 0.97 (0.81-1.17) 0.97 (0.81-1.17) 0.87 (0.62-1.21) 0.97 (0.88-1.07)
 Other 0.89 (0.71-1.11) 0.76 (0.50-1.16) 0.76 (0.50-1.16) 0.49 (0.20-1.19) 0.90 (0.73-1.10)
Maternal Tobacco Use 1.03 (0.93-1.15) 1.04 (0.86-1.24) 1.05 (0.86-1.29) 1.23 (0.86-1.76) 1.03 (0.93-1.15)
Diabetes 0.92 (0.80-1.05) 1.03 (0.82-1.30) 1.12 (0.87-1.44) 1.08 (0.60-1.95) 0.92 (0.79-1.06)
Preeclampsia 1.07 (0.96-1.19) 1.08 (0.91-1.28) 1.04 (0.86-1.25) 1.05 (0.72-0.53) 1.06 (0.94-1.19)
Chronic Hypertension 1.06 (0.95-1.19) 1.09 (0.91-1.31) 1.08 (0.89-1.32) 1.22 (0.83-1.77) 1.11 (0.99-1.25)
PPROMd 0.91 (0.78-1.06) 0.81 (0.67-0.99) 0.85 (0.68-1.08) 0.82 (0.56-1.20) 0.89 (0.76-1.04)
Days Between Last BMZf Dose and Delivery 1.00 (1.00-1.00) 1.00 (0.98-1.02) 0.99 (0.94-1.04) 1.02 (0.91-1.16) 1.00 (1.00-1.00)
Total Doses of BMZ 1.06 (0.99-1.13) 1.01 (0.92-1.12) 1.00 (0.89-1.11) 1.14 (0.91-1.41) 0.83 (0.66-1.05)
Delivery Type
 Vaginal Reference Reference    
 Cesarean without labor 1.14 (1.03-1.27) 1.13 (0.96-1.34) 1.14 (0.95-+1.38) 1.45 (1.07-1.98) 1.14 (1.03-1.27)
 Cesarean with labor 1.25 (1.07-1.46) 1.42 (1.13-1.79) 1.36 (1.05-1.78) 2.08 (1.16-3.72) 1.24 (1.02-1.50)
  1. aOdds ratios of maternal and prenatal factors by multivariable regression with adjustment for GA at delivery
  2. bThe subcohort refers to women who delivered within 14 days of receiving their last BMZ dose
  3. cBody mass index (BMI) reported in kg/m2
  4. dPreterm premature rupture of membranes (PPROM)
  5. eGestational age (GA)
  6. fBetamethasone (BMZ)