Table 4 Multivariable logistic regression analysis on potential risk factors for pregnancy outcomes in GnRH-ant protocol (n = 918)
Potential risk factor variables | Adjusted OR* (95% CI) | P-value |
|---|---|---|
Clinical pregnancy | ||
 FET timing (Immediate FETa versus delayed FETb) | 0.956 (0.721–1.267) | NS |
 Age (35–37 versus ≤34) | 0.798 (0.502–1.269) | NS |
 Age (≥38 versus ≤34) | 0.386 (0.210–0.708) | P < 0.01 |
 BMI (< 18.5 versus 18.5–24.9) | 0.781 (0.424–1.440) | NS |
 BMI (≥25 versus 18.5–24.9) | 0.981 (0.731–1.315) | NS |
 Trigger type (GnRH-a trigger versus HCG trigger) | 1.229 (0.891–1.695) | NS |
 Trigger type (Double trigger versus HCG trigger) | 2.560 (1.143–5.737) | P < 0.05 |
 Insemination method (ICSI versus IVF) | 1.006 (0.696–1.453) | NS |
 Number of embryo transferred (2 versus 1) | 1.726 (1.040–2.865) | P < 0.05 |
 Embryo stage (blastocyst versus cleavage) | 3.062 (1.871–5.011) | P < 0.001 |
 Top or good quality embryo transfer (yes versus no) | 0.984 (0.647–1.497) | NS |
 Tubal factor (yes versus no) | 1.043 (0.745–1.461) | NS |
 Ovulatory disorder (yes versus no) | 1.242 (0.909–1.695) | NS |
 Male factor (yes versus no) | 1.012 (0.720–1.423) | NS |
 Unexplained factor (yes versus no) | 1.268 (0.622–2.585) | NS |
Spontaneous abortion | ||
 FET timing (Immediate FETa versus delayed FETb) | 0.645 (0.430–0.966) | P < 0.05 |
 Age (35–37 versus ≤34) | 1.202 (0.620–2.329) | NS |
 Age (≥38 versus ≤34) | 1.511 (0.696–3.280) | NS |
 BMI (< 18.5 versus 18.5–24.9) | 0.716 (0.245–2.095) | NS |
 BMI (≥25 versus 18.5–24.9) | 1.400 (0.934–2.100) | NS |
 Trigger type (GnRH-a trigger versus HCG trigger) | 0.907 (0.570–1.445) | NS |
 Trigger type (Double trigger versus HCG trigger) | 1.408 (0.613–3.232) | NS |
 Insemination method (ICSI versus IVF) | 1.274 (0.756–2.144) | NS |
 Number of embryo transferred (2 versus 1) | 1.036 (0.553–1.943) | NS |
 Embryo stage (blastocyst versus cleavage) | 1.537 (0.830–2.845) | NS |
 Top or good quality embryo transfer (yes versus no) | 0.971 (0.538–1.753) | NS |
 Tubal factor (yes versus no) | 0.847 (0.550–1.389) | NS |
 Ovulatory disorder (yes versus no) | 1.583 (1.017–2.465) | P < 0.05 |
 Male factor (yes versus no) | 0.793 (0.483–1.304) | NS |
 Unexplained factor (yes versus no) | 0.978 (0.353–2.710) | NS |
Live birth | ||
 FET timing (Immediate FETa versus delayed FETb) | 1.220 (0.925–1.608) | NS |
 Age (35–37 versus ≤34) | 0.761 (0.479–1.210) | NS |
 Age (≥38 versus ≤34) | 0.249 (0.121–0.514) | P < 0.001 |
 BMI (< 18.5 versus 18.5–24.9) | 0.883 (0.484–1.609) | NS |
 BMI (≥25 versus 18.5–24.9) | 0.798 (0.599–1.063) | NS |
 Trigger type (GnRH-a trigger versus HCG trigger) | 1.250 (0.916–1.707) | NS |
 Trigger type (Double trigger versus HCG trigger) | 1.867 (0.951–3.664) | NS |
 Insemination method (ICSI versus IVF) | 0.939(0.655–1.347) | NS |
 Number of embryo transferred (2 versus 1) | 1.637 (1.027–2.610) | P < 0.05 |
 Embryo stage (blastocyst versus cleavage) | 2.409 (1.533–3.785) | P < 0.001 |
 Top or good quality embryo transfer (yes versus no) | 1.052 (0.701–1.580) | NS |
 Tubal factor (yes versus no) | 1.144 (0.825–1.588) | NS |
 Ovulatory disorder (yes versus no) | 0.994 (0.734–1.345) | NS |
 Male factor (yes versus no) | 1.154 (0.827–1.611) | NS |
 Unexplained factor (yes versus no) | 1.232 (0.619–2.450) | NS |