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Table 2 Analysis of association between SGA twin newborns and neonatal outcomes based on singleton birthweight reference

From: Should singleton birth weight standards be applied to identify small-for-gestational age twins?: analysis of a retrospective cohort study

Outcomes

Non-SGA

(n = 4,052)

SGA

(n = 2,002)

Unadjusted OR (95 % CI)

P-value

Adjusted OR (95 % CI)a

P-value

Neonatal unit admission

1629 (40.2)

878 (43.9)

1.31 (1.20–1.44)

< 0.001

2.11 (1.84–2.41)

< 0.001

Neonatal jaundice

1191 (29.4)

627 (31.3)

1.27 (1.15–1.40)

< 0.001

1.99 (1.73–2.29)

< 0.001

NRDS

413 (10.2)

120 (6.0)

0.82 (0.72–0.94)

0.004

1.11 (0.88–1.41)

0.376

Neonatal asphyxia

108 (2.7)

34 (1.7)

0.70 (0.49–0.99)

0.045

0.96 (0.63–1.44)

0.828

Ventilator support

351 (8.7)

110 (5.5)

0.78 (0.65–0.94)

0.008

1.45 (1.09–1.91)

0.010

HIE

12 (0.3)

6 (0.3)

1.01 (0.38–2.70)

0.980

1.04 (0.38–2.86)

0.934

ICH

17 (0.4)

8 (0.4)

0.97 (0.42–2.26)

0.941

1.09 (0.46–2.61)

0.846

Sepsis

50 (1.2)

18 (0.9)

0.76 (0.44–1.30)

0.312

1.20 (0.67–2.14)

0.533

BPD

50 (1.2)

14 (0.7)

0.66 (0.37–1.17)

0.157

1.61 (0.80–3.21)

0.180

Neonatal death

16 (0.4)

8 (0.4)

1.01 (0.43–2.37)

0.982

1.39 (0.56–3.45)

0.475

Severe composite outcome

101 (2.5)

28 (1.4)

0.67 (0.45-1.00)

0.051

1.34 (0.83–2.16)

0.230

  1. aAdjusted for gestational age at delivery, nulliparity, maternal age, chorionicity, use of ART, PE and GDM. NRDS, neonatal respiratory distress syndrome; HIE hypoxic ischemic encephalopathy, ICH intracranial hemorrhage, BPD bronchopulmonary dysplasia, OR odds ratio, ART assisted reproductive technology, PE pre-eclampsia, GDM, gestational diabetes mellitus