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Table 2 Analysis of association between SGA twin newborns and neonatal outcomes based on singleton birthweight reference

From: Should singleton birth weight standards be applied to identify small-for-gestational age twins?: analysis of a retrospective cohort study

Outcomes Non-SGA
(n = 4,052)
SGA
(n = 2,002)
Unadjusted OR (95 % CI) P-value Adjusted OR (95 % CI)a P-value
Neonatal unit admission 1629 (40.2) 878 (43.9) 1.31 (1.20–1.44) < 0.001 2.11 (1.84–2.41) < 0.001
Neonatal jaundice 1191 (29.4) 627 (31.3) 1.27 (1.15–1.40) < 0.001 1.99 (1.73–2.29) < 0.001
NRDS 413 (10.2) 120 (6.0) 0.82 (0.72–0.94) 0.004 1.11 (0.88–1.41) 0.376
Neonatal asphyxia 108 (2.7) 34 (1.7) 0.70 (0.49–0.99) 0.045 0.96 (0.63–1.44) 0.828
Ventilator support 351 (8.7) 110 (5.5) 0.78 (0.65–0.94) 0.008 1.45 (1.09–1.91) 0.010
HIE 12 (0.3) 6 (0.3) 1.01 (0.38–2.70) 0.980 1.04 (0.38–2.86) 0.934
ICH 17 (0.4) 8 (0.4) 0.97 (0.42–2.26) 0.941 1.09 (0.46–2.61) 0.846
Sepsis 50 (1.2) 18 (0.9) 0.76 (0.44–1.30) 0.312 1.20 (0.67–2.14) 0.533
BPD 50 (1.2) 14 (0.7) 0.66 (0.37–1.17) 0.157 1.61 (0.80–3.21) 0.180
Neonatal death 16 (0.4) 8 (0.4) 1.01 (0.43–2.37) 0.982 1.39 (0.56–3.45) 0.475
Severe composite outcome 101 (2.5) 28 (1.4) 0.67 (0.45-1.00) 0.051 1.34 (0.83–2.16) 0.230
  1. aAdjusted for gestational age at delivery, nulliparity, maternal age, chorionicity, use of ART, PE and GDM. NRDS, neonatal respiratory distress syndrome; HIE hypoxic ischemic encephalopathy, ICH intracranial hemorrhage, BPD bronchopulmonary dysplasia, OR odds ratio, ART assisted reproductive technology, PE pre-eclampsia, GDM, gestational diabetes mellitus