Association between premature ovarian insufficiency and gut microbiota

Table 1 Demographic and clinical characteristics of the two groups

Characteristic	POI = 35	NG = 18	P value
Age (years)	35.23 ± 4.62	33.5 ± 4.05	0.19
BMI (kg/m²)	21.5 ± 1.35	20.54 ± 1.61	0.02*
FSH (mIU/mL)	45.60 ± 28.77	5.39 ± 1.74	< 0.01**
LH (mIU/mL)	15.79 ± 9.02	4.04 ± 1.07	< 0.01**
E2 (pg/L)	30.71 ± 11.7	54.56 ± 9.0	< 0.01**
P (nmol/L)	0.48 ± 0.33	0.35 ± 0.14	0.12
T (nmol/L)	0.43 ± 0.22	0.31 ± 0.11	0.03*
PRL (nmol/L)	14.37 ± 7.12	11.49 ± 4.57	0.13
AMH (ng/mL)	0.49 ± 0.35	3.94 ± 2.04	< 0.01**
FSH/LH (ratio)	2.88 ± 0.68	1.32 ± 0.18	< 0.01**
GLU (nmol/L)	5.07 ± 0.41	4.99 ± 0.32	0.48

BMI body mass index, FSH follicle-stimulating hormone, LH luteinizing hormone, E2 estradiol, P progesterone, T testosterone, PRL prolactin, AMH anti-Mullerian hormone, GLU glucose
*P <0.05; **P < 0.01

ISSN: 1471-2393