Table 2 Comparison of clinical outcomes between the two groups in fresh cycles
Groups | GnRH antagonist group | Depot GnRH agonist group | P values |
|---|---|---|---|
Cycles (n) | 502 | 617 | |
Duration of Gn stimulation (day) | 10.23 ± 2.39 | 12.94 ± 1.94 | <0.05 |
Total dosage of Gn (IU) | 2423.16 ± 935.68 | 3046.44 ± 876.29 | <0.05 |
Number of oocytes retrieved | 9.97 ± 4.1 | 16.23 ± 3.8 | <0.05 |
Number of transferred embryos | 1.85 ± 0.78 | 1.87 ± 0.83 | >0.05 |
High-quality embryo rate (%) | 61.47 %(2616/4256) | 56.24 %(4872/8663) | >0.05 |
Clinical pregnancy rate (%) | 37.27 %(131/352) | 54.89 %(170/310) | <0.05 |
Abortion rate (%) | 18.32 %(24/131) | 10.58 %(18/170) | <0.05 |
Moderate and severe OHSS (%) | 8.37 %(42/502) | 13.12 %(81/617) | <0.05 |