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Table 2 Differential diagnosis of megaduodenum

From: Prenatal diagnosis of megaduodenum using ultrasound: a case report

Differential diagnosis

Time of discovery

Stomach size

Communication between the mass and stomach

Amniotic fluid

Mass characteristics

Other manifestations on ultrasound

Megaduodenum

Can be found during early pregnancy

Normal

Yes

Normal

Enlargement with gestational week, irregular shape, echogenic wall

Duodenal stenosis or atresia [11, 12]

Usually found during the second trimester

Dilated

Yes

Often accompanied by polyhydramnios

Spherically dilated duodenum

“Double-bubble” sign, a shriveled bowel can sometimes be observed at the distal end

Meconium pseudocyst [13, 14]

Mid-to-late pregnancy

Normal

No

Often accompanied by polyhydramnios

Large cystic mass with echogenic walls and some septa

Ascites, scattered intra-abdominal calcifications