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Table 4 Uni- and multivariable Poisson regression analysis of death risks of the whole Huai’an region

From: Correction to: A birth population-based survey of preterm morbidity and mortality by gestational age

A. The total preterm births

Variables

Category

All-death

n (%)

Univariable

RR (95% CI)

Multivariable

RR (95% CI)

Born in HWCH

No

138 (9.1)

  

Yes

114 (10.0)

1.10 (0.87–1.39)

0.65 (0.52–0.82)3

PROM

No

192 (10.5)

  

Yes

60 (7.3)

0.69 (0.53–0.92)1

1.09 (0.88–1.35)

HDP

No

215 (9.7)

  

Yes

37 (8.5)

0.88 (0.63–1.22)

1.13 (0.86–1.48)

GDM

No

239 (9.5)

  

Yes

13 (10.6)

1.12 (0.66–1.90)

1.39 (0.92–2.12)

Anemia

No

228 (10.0)

  

Yes

24 (6.4)

0.64 (0.43–0.96)1

0.84 (0.63–1.12)

ANG

No

182 (11.8)

  

Yes

70 (6.3)

0.54 (0.41–0.70)3

0.49 (0.27–0.74)1

Cesarean delivery

No

186 (16.7)

  

Yes

66 (4.3)

0.26 (0.20–0.34)3

0.73 (0.56–0.96)1

Male

No

110 (9.7)

  

Yes

140 (9.2)

0.95 (0.75–1.21)

0.96 (0.81–1.15)

GA, weeks

34–36

63 (3.5)

  

32–33

35 (8.2)

2.37 (1.59–3.53)3

1.15 (0.74–1.77)

28–31

93 (29.6)

8.58 (6.38–11.5)3

1.66 (1.10–2.51)1

25–27

61 (71.8)

20.8 (15.8–27.4)3

1.67 (1.02–2.72)1

BW, g

>  2500

43 (3.3)

  

1500-2499

81 (7.5)

2.25 (1.57–3.23)3

0.96 (0.65–1.41)

1000-1499

63 (31.0)

9.35 (6.54–13.4)3

1.23 (0.77–1.95)

<  1000

65 (94.2)

28.4 (21.0–38.3)3

2.25 (1.38–3.67)2

Multiple births

No

205 (10.0)

  

Yes

47 (7.8)

0.78 (0.57–1.05)

0.98 (0.78–1.25)

SGA

No

199 (7.9)

  

Yes

24 (20.5)

2.58 (1.76–3.78)3

1.09 (0.79–1.51)

AF contamination

No

191 (7.8)

  

Yes

61 (30.5)

3.91 (3.05–5.02)3

1.46 (1.16–1.84)2

5-min Apgar < 7

No

49 (2.1)

  

Yes

203 (61.3)

29.0 (21.7–38.8)3

14.7 (9.63–22.5)3

Birth defects

No

219 (8.5)

  

Yes

33 (40.7)

4.78 (3.57–6.40)3

1.73 (1.28–2.33)3

B. The hospitalized preterm infants

Variables

Category

In-hospital deaths

n (%)

Univariable

RR (95% CI)

Multivariable

RR (95% CI)

Admitted in HWCH

No

31 (3.4)

  

Inborn

33 (4.1)

1.22 (0.75–1.97)

0.96 (0.58–1.58)

Out-born

23 (10.3)

3.05 (1.81–5.12)3

2.27 (1.40–3.69)2

Male

No

48 (5.7)

  

Yes

39 (3.6)

0.63 (0.42–0.95)1

0.73 (0.50–1.07)

GA, weeks

34–36

15 (1.2)

  

32–33

12 (3.3)

2.90 (1.37–6.14)2

1.49 (0.68–3.26)

28–31

38 (15.8)

13.7 (7.65–24.5)3

2.31 (1.02–5.26)1

25–27

22 (55.0)

47.7 (26.8–84.9)3

2.44 (0.90–6.61)

BW, g

>  2500

9 (1.1)

  

1500-2499

23 (2.5)

2.23 (1.04–4.78)1

0.95 (0.40–2.25)

1000-1499

41 (23.8)

21.6 (10.7–43.5)3

2.25 (0.83–6.13)

<  1000

14 (70.0)

63.3 (31.1–128)3

3.66 (1.16–11.6)1

Cesarean delivery

No

58 (7.5)

  

Yes

29 (2.5)

0.33 (0.21–0.51)3

0.53 (0.34–0.83)2

5-min Apgar < 7

No

47 (2.6)

  

Yes

40 (24.0)

9.04 (6.12–13.4)3

2.73 (1.75–4.26)3

Birth defects

No

67 (3.7)

  

Yes

20 (13.0)

3.46 (2.16–5.55)3

2.57 (1.59–4.16)3

Admitted within 24 h (after birth)

No

8 (2.1)

  

Yes

79 (5.0)

2.35 (1.15–4.82)1

0.81 (0.39–1.69)

RDS

No

29 (1.7)

  

Yes

58 (21.2)

12.2 (7.97–18.7)3

2.76 (1.65–4.65)3

Pneumonia/sepsis

No

20 (1.7)

  

Yes

67 (8.6)

5.02 (3.07–8.20)3

0.74 (0.43–1.28)

NEC

No

72 (3.8)

  

Yes

15 (39.5)

10.4 (6.62–16.4)3

1.76 (1.03–3.03)1

Surfactant

No

50 (2.9)

  

Yes

37 (17.1)

5.88 (3.94–8.78)3

0.43 (0.28–0.66)3

NIV/MV

No

6 (0.5)

  

Yes

81 (10.5)

20.4 (8.93–46.4)3

6.69 (2.07–21.7)2

  1. Values are presented as number of deaths (%) and corresponding relative risk (RR) and its 95% confidence intervals (95% CI) by Poisson regression analysis. Multivariable analysis was done by all listed factors in the first column. For definition of all-death see Table 1 legends, note 6; for definition of in-hospital deaths see Table 1 legends, note 5; for other definitions and abbreviations see Table 1 and 3 legends as reference
  2. 1, 2 and 3 stands for P < 0.05, P < 0.01 and P < 0.001, respectively