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Table 2 Factors associated with mother to child HIV transmission

From: Towards elimination of mother‐to‐child transmission of HIV in Rwanda: a nested case‐control study of risk factors for transmission

 

Bivariate analysis

Multivariable analysis

OR

95 % CI

aOR

95 % CI

Age group of mothers (years)

  below 24 (ref)

1

-

  

  25–34

0.51

0.25–1.06

  

  above 35

0.59

0.23–1.58

  

Viral load suppression

  suppressed (< 1000 copies/ml) (ref)

1

-

1

-

  not suppressed ( > = 1000 copies/ml)

2.96*

1.43–6.14

1.95

0.61–6.27

  missing

4.17*

1.75–9.91

1.88

0.53–6.70

Marital status

  married (ref)

1

-

1

-

  single

8.23**

2.92–23.22

6.93*

1.53–31.30

  cohabitating

4.33**

1.88–9.99

3.89

0.92–16.43

  divorced/separated

2.53

0.89–7.19

1.07

0.21–5.50

Occupation

  employed (ref)

1

-

  

  not employed

1.36

0.61–3.05

  

Parity before the current pregnancy

  1–2 children (ref)

1

-

1

-

  no child

2.75*

1.46–5.15

1.86

0.65–5.35

  3 and more

0.74

0 0.29-1.89

1.61

0.45–5.75

Accompaniment by partner during any antenatal care visit

  yes (ref)

1

-

1

-

  no

4.80**

2.52–9.17

1.93

0.72–5.22

  not documented

2.93

0.96–8.87

1.03

0.16–6.62

Initiation of ART

  before pregnancy (ref)

1

-

1

-

  first or second trimester of pregnancy

1.58

0.64–3.89

2.15

0.68–6.79

  third trimester of pregnancy

7.27**

2.40-22.04

7.13**

1.82–27.90

  during or after labor

16.43**

6.16–43.75

8.97**

2.38–33.69

Place of delivery

  health facility (ref)

1

-

1

-

  home

4.43*

1.83–10.75

1.41

0.27–7.46

ART prophylaxis for the child at birth

  yes (ref)

1

-

1

-

  no

9.54**

4.23–21.51

5.76**

1.62–20.47

Retained in care during pregnancy or breastfeeding period

  yes (ref)

1

-

1

-

  no

4.17*

1.59–10.96

2.44

0.53–11.24

Mode of delivery

  vaginal delivery (ref)

1

-

  

  caesarean section

1.64

0.73–3.68

  

Year of birth of child

  2013 (ref)

1

-

  

  2014

0.93

0.10–8.63

  

  2015

0.61

0.07–5.24

  
  1. *p-value < 0.05, **p-value < 0.001