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Table 4 Characteristics of newborns exposed to SARS-CoV-2 during gestation by prematurity

From: SARS-COV-2 infection in pregnant women and newborns in a Spanish cohort (GESNEO-COVID) during the first wave

 

Newbornsa

No preterm

Preterm

p-value*

OR

N = 107

N = 72

N = 32

  

Men

47 (46.7%)

44 (53.0%)

12 (57.1%)

0.968

0.87 [0.32;2.31]

Breastfeed

   

0.003

 

Maternal

71 (66.4%)

59 (72.8%)

9 (42.9%)

 

Ref.

Artificial

18 (16.8%)

9 (11.1%)

9 (42.9%)

 

6.33 [1.97;21.2]

Mixed

16 (15.0%)

13 (16.0%)

3 (14.3%)

 

1.54 [0.29;6.21]

Apgar 1’

9.00 [9.00;9.00]

9.00 [9.00;9.00]

9.00 [8.00;9.00]

0.054

0.63 [0.39;1.02]

Apgar 5’

10.0 [10.0;10.0]

10.0 [10.0;10.0]

10.0 [9.00;10.0]

0.009

0.52 [0.28;0.98]

Small for GA

6 (5.61%)

5 (6.02%)

1 (4.76%)

1.000

0.86 [0.03;6.05]

Symptomatology

81 (75.7%)

69 (83.1%)

9 (42.9%)

< 0.001

0.16 [0.05;0.44]

Need of NICU Admission

18 (16.8%)

6 (7.23%)

12 (57.1%)

< 0.001

17.6 [5.36;65.4]

Days at NICU

3.00 [1.00;8.00]

1.00 [0.50;1.50]

6.50 [2.75;14.8]

0.015

1.61 [0.91;2.85]

Oxygen need

13 (12.1%)

4 (4.82%)

9 (42.9%)

0.203

3.44 [0.54;26.6]

Days of oxygen

6.00 [1.00;19.0]

5.50 [1.00;10.8]

9.00 [1.00;29.0]

0.470

1.05 [0.95;1.16]

Surfactant need

6 (5.61%)

1 (1.20%)

5 (23.8%)

0.333

3.70 [0.40;118]

RT-PCR at birth

   

0.344

 

Negative

101 (94.4%)

77 (92.8%)

21 (100%)

 

Ref.

Not realized

6 (5.61%)

6 (7.23%)

0 (0.00%)

  

RT-PCR at 15 days

   

0.700

 

Negative

60 (56.1%)

44 (53.0%)

13 (61.9%)

0.700

Ref.

Positive

1 (0.93%)

1 (1.20%)

0 (0.00%)

  
  1. D Days, GA Gestational age, RT-PCR Real Time- Polymerase Chain Reaction. aGestational age information of three newborns was not available. *p-value was calculated using Chi-squared or Fisher test for categorical variables and U-Mann Whitney for continuous variables