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Table 5 Stratified sensitivity analyses of the adjusted association of pregnancy with hospitalization, maximum length of hospital stay, moderate ventilation, invasive ventilation, and death, among COVID-19 associated female patients (18–44 years old)

From: The risk of clinical complications and death among pregnant women with COVID-19 in the Cerner COVID-19 cohort: a retrospective analysis

Variables

Hospitalization

Max LOS

(< 1 Day)

Max LOS

(> = 1 Day)

Moderate Ventilation

Invasive Ventilation

Death

aOR (95% CI)

\( {e}^{\hat{\beta}} \) (95% CI)

\( {e}^{\hat{\beta}} \) (95% CI)

aOR (95% CI)

aOR (95% CI)

aOR (95% CI)

Age (Years)

 18–34

12.79 (10.94, 14.94)1

1.74 (1.62, 1.87)

0.92 (0.86, 0.98)

1.06 (0.24, 4.66)

0.93 (0.53, 1.63)

0.65 (0.20, 2.18)

 35–44

11.71 (8.63, 15.88)

1.90 (1.63, 2.22)

0.93 (0.82, 1.06)

3.74 (1.65, 8.52)

0.93 (0.43, 2.03)

1.10 (0.15, 8.28)

Race and Ethnicity

 Non-Hispanic White

12.64 (9.79, 16.32)

1.89 (1.63, 2.20)

0.89 (0.80, 0.99)

1.62 (0.60, 4.37)

1.17 (0.52, 2.61)

0.75 (0.10, 5.77)

 Non-Hispanic American Indian or Alaska Native

13.15 (3.46, 50.02)

1.75 (0.74, 4.15)

0.49 (0.28, 0.84)

-2

–

8.08 (0.56, 115.45)

 Non-Hispanic Asian or Pacific Islander

12.58 (5.14, 30.76)

1.71 (1.01, 2.89)

0.76 (0.54, 1.06)

–

–

–

 Non-Hispanic Black or African American

9.85 (7.12, 13.63)

1.55 (1.35, 1.79)

0.89 (0.77, 1.03)

4.51 (1.96, 10.39)

1.54 (0.64, 3.72)

1.46 (0.18, 12.07)

 Non-Hispanic Other

15.14 (10.08, 22.75)

2.22 (1.81, 2.74)

0.91 (0.81, 1.03)

6.40 (2.68, 15.28)

1.19 (0.45, 3.13)

0.59 (0.07, 4.79)

 Hispanic or Latino

11.77 (9.33, 14.86)

1.72 (1.57, 1.89)

0.97 (0.87, 1.07)

1.63 (0.55, 4.78)

1.04 (0.43, 2.48)

–

Insurance

 Private

16.23 (13.12, 20.08)

1.79 (1.64, 1.96)

0.96 (0.88, 1.05)

3.81 (1.89, 7.66)

1.18 (0.58, 2.40)

0.59 (0.07, 4.70)

 Government/Misc

8.05 (3.31, 19.58)

1.40 (0.91, 2.17)

1.02 (0.69, 1.51)

–

–

–

 Medicaid

9.75 (7.79, 12.22)

1.75 (1.55, 1.97)

0.88 (0.80, 0.97)

2.87 (1.40, 5.88)

1.52 (0.80, 2.89)

1.38 (0.39, 4.82)

 Medicare

3.16 (0.84, 11.83)

1.30 (0.68, 2.46)

2.00 (0.92, 4.35)

–

–

–

 Self-Pay

10.05 (6.14, 16.47)

1.93 (1.58, 2.35)

1.03 (0.84, 1.27)

5.55 (1.54, 20.00)

–

–

 Missing

11.64 (6.93, 19.54)

1.82 (1.31, 2.51)

0.82 (0.71, 0.96)

0.58 (0.07, 4.47)

0.86 (0.30, 2.46)

–

Elixhauser AHRQ weighted Comorbidity Index

  < 0

10.96 (8.29, 14.50)

1.80 (1.54, 2.11)

0.87 (0.78, 0.96)

3.41 (1.42, 8.17)

0.96 (0.33, 2.80)

–

 0

24.46 (19.93, 30.02)

1.79 (1.65, 1.94)

0.95 (0.88, 1.03)

3.41 (1.06, 10.98)

1.05 (0.31, 3.54)

–

 1–4

9.10 (5.57, 14.87)

1.55 (1.25, 1.92)

0.93 (0.74, 1.16)

3.67 (1.02, 13.18)

0.98 (0.23, 4.21)

–

  > =5

3.15 (2.29, 4.34)

1.68 (1.39, 2.03)

0.94 (0.82, 1.07)

2.00 (1.07, 3.75)

1.03 (0.59, 1.80)

1.07 (0.38, 3.07)

Diabetes History

  No

12.12 (10.55, 13.92)

1.78 (1.67, 1.90)

0.88 (0.83, 0.93)

3.14 (1.92, 5.14)

1.03 (0.64, 1.67)

1.27 (0.45, 3.61)

  Yes

10.81 (4.66, 25.07)

2.30 (1.24, 4.26)

0.97 (0.73, 1.29)

–

0.59 (0.14, 2.58)

–

  1. 1 Odds/percentage change of column outcome for those pregnant compared to those not among row group, adjusted for all other predictors in Table 3 for sufficient sample sizes, COVID-19 medications and disease history (upon need) removed for insufficient sample sizes;
  2. 2 “-“=Insufficient sample size