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Table 2 Clinical characteristics of COVID-19 associated female patients (18–44 years old) by pregnancy status

From: The risk of clinical complications and death among pregnant women with COVID-19 in the Cerner COVID-19 cohort: a retrospective analysis

Characteristic

Pregnant1

n(%2)

Not Pregnant

n(%2)

p-value4

Total

1609

20,884

 

History of chronic diseases7

 Congestive heart failure

9 (0.6)

359 (1.7)

< 0.0015

 Cardiac arrhythmias

167 (10.4)

2224 (10.7)

0.74

 Valvular disease

22 (1.4)

299 (1.4)

0.91

 Pulmonary circulation disorders

12 (0.7)

344 (1.7)

0.01

 Peripheral vascular disorders

2 (0.1)

248 (1.2)

< 0.0015

 Hypertension, uncomplicated

104 (6.5)

2355 (11.3)

< 0.001

 Hypertension, complicated

7 (0.4)

412 (2.0)

< 0.0015

 Paralysis

0 (0.0)

141 (0.7)

< 0.0015

 Other neurological disorders

35 (2.2)

904 (4.3)

< 0.001

 Chronic pulmonary disease

203 (12.6)

3640 (17.5)

< 0.001

 Diabetes, uncomplicated

48 (3.0)

1392 (6.7)

< 0.001

 Diabetes, complicated

17 (1.1)

766 (3.7)

< 0.001

 Hypothyroidism

81 (5.0)

1042 (5.0)

> 0.99

 Renal failure

2 (0.1)

353 (1.7)

< 0.0015

 Liver disease

26 (1.6)

948 (4.6)

< 0.001

 Peptic ulcer disease

3 (0.2)

138 (0.7)

0.015

 AIDS/HIV

4 (0.2)

72 (0.3)

0.665

 Lymphoma

0 (0.0)

49 (0.2)

0.0485

 Metastatic cancer

1 (0.1)

82 (0.4)

0.035

 Solid tumor without metastasis

9 (0.6)

244 (1.2)

0.03

 Rheumatoid arthritis/collagen vascular diseases

16 (1.0)

459 (2.2)

0.002

 Coagulopathy

71 (4.4)

636 (3.1)

0.003

 Obesity

331 (20.6)

3567 (17.1)

< 0.001

 Weight loss

14 (0.9)

391 (1.9)

0.01

 Fluid and electrolyte disorders

265 (16.5)

3313 (15.9)

0.58

 Blood loss anemia

15 (0.9)

196 (0.9)

> 0.99

 Deficiency anemia

88 (5.5)

1021 (4.9)

0.34

 Alcohol abuse

15 (0.9)

502 (2.4)

< 0.001

 Drug abuse

85 (5.3)

1176 (5.6)

0.58

 Psychoses

14 (0.9)

304 (1.5)

0.07

 Depression

42 (2.6)

734 (3.5)

0.06

Elixhauser AHRQ weighted comorbidity (continuous score)

0 (0–0)3

0 (0–3)3

0.0016

Elixhauser AHRQ weighted comorbidity (categorical score)

  

< 0.001

  < 0

386 (24.0)

4166 (19.9)

 

 0

822 (51.1)

11,031 (52.8)

 

 1–4

116 (7.2)

2237 (10.7)

 

  > =5

285 (17.7)

3450 (16.5)

 

COVID-19 Medications

 Hydroxychloroquine

38 (2.4)

525 (2.5)

0.77

 Remdesivir

3 (0.2)

39 (0.2)

> 0.99

 Decadron or Prednisone

36 (2.2)

1029 (4.9)

< 0.001

 Aspirin and Plavix

0 (0.0)

22 (0.1)

0.40

 Other anticoagulant

219 (13.6)

1721 (8.2)

< 0.001

History of Gestational Diabetes

163 (10.1)

411 (2.0)

< 0.001

  1. 1 Defined by ICD-9 and ICD-10 codes; 2% = column percentage; 3 median (Q1-Q3)
  2. 4 Chi-square test (unless otherwise noted); 5 Fisher’s Exact test
  3. 6 Wilcoxon Rank-Sum Test; 7 Up till January 1, 2015 (these are the diseases that make up the Elixhauser comorbidity index);