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Table 1 The Swansea Criteria for diagnosis of AFLP and the Tennessee Classification System for diagnosis of HELLP syndrome

From: Comparison of maternal and neonatal outcomes between acute fatty liver of pregnancy and hemolysis, elevated liver enzymes and low platelets syndrome: a retrospective cohort study

Swansea Criteria

Tennessee Classification System

Vomiting

AST > 70 IU/L

Abdominal pain

LDH > 600 IU/L 

Polydipsia or polyuria

Platelet < 100,000/µL 

Encephalopathy

 

Leukocytosis (> 11 × 106/mL)

 

Hypoglycemia (< 72 mg/dL)

 

Hyperbilirubinemia (> 0.8 mg/dL)

 

Impaired liver function (AST or ALT > 42 IU/L)

 

Hyperuricemia (> 5.7 mg/dL)

 

Hyperammonemia (> 66 µg/dL)

 

Impaired renal function (creatinine > 1.7 mg/dL)

 

Coagulopathy (PT > 14 s or aPTT > 34 s)

 

Ascites or bright liver on ultrasound scan

 

Microvesicular steatosis on liver biopsy

 
  1. AFLP acute fatty liver of pregnancy; HELLP hemolysis, elevated liver enzymes and low platelets; AST aspartate transaminase; ALT alanine aminotransferase; PT prothrombin time; aPTT activated partial thromboplastin time; LDH lactate dehydrogenase