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Table 2 Categorized analysis between parental pre-pregnancy BMI and newborn TL

From: Maternal overweight but not paternal overweight before pregnancy is associated with shorter newborn telomere length: evidence from Guangxi Zhuang birth cohort in China

All (n = 1082) Unadjusted Model A Model B
Percentage change (95% CI) P-value Percentage change (95% CI) P-value Percentage change (95% CI) P-value
Maternal BMI
 NW Ref Ref Ref
 UW −0.23(−4.50,4.23) 0.937 0.23(−4.28,4.71) 0.958 0.23(−4.28,4.95) 0.929
 OW −7.96(−14.49, − 0.92) 0.029 −8.17(− 14.89, − 0.92) 0.026 − 7.96(− 14.49, − 0.69) 0.032
Paternal BMI
 HW Ref   Ref   Ref  
 OW 0.69(−6.03,7.65) 0.850 0.93(−5.59,8.14) 0.785 0.93(−5.59,8.14) 0.772
Parents’ weight status combination
 Both parents HW Ref   Ref   Ref  
 OW father, HW mother 0.46(−6.24,7.89) 0.892 0.69(−6.24,7.89) 0.869 0.69(−6.24,8.14) 0.866
 OW mother, HW father −8.17(−14.89, −0.92) 0.030 − 8.59(− 15.67, − 1.14) 0.024 −8.38(− 15.47, − 0.92) 0.028
 Both parents OW −4.50(−23.97,20.23) 0.698 −3.39(− 23.26,21.62) 0.768 −2.50(−22.55,22.74) 0.830
  1. Abbreviation: BMI Body mass index, TL Telomere length, UW Underweight, NW Normal weight, HW Healthy weight (normal and underweight), OW Overweight
  2. Model A: adjusted for parental age, newborn factors (sex, gestational age and birth weight)
  3. Model B: Model A + maternal factors (residential place, gravidity, parity, drinking before pregnancy, passive smoking during pregnancy, pregnancy comorbidities or complications, and cesarean section)
  4. Estimates are presented as a percentage change in average relative telomere length