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Table 1 The characteristics of the study group in the DNA methylation analysis by delivery mode

From: The impact of cesarean delivery on infant DNA methylation

  DNA methylation chip analysis DNA methylation validation analysis
VD (n = 30) CDMR (n = 30) p VD (n = 40) CDMR (n = 40) p
Gestational age (weeks)   1.00    0.14
 37 2 (6.7) 1 (3.3)   2 (5.0) 1 (2.5)  
 38 8 (26.7) 7 (23.3)   7 (17.5) 11 (27.5)  
 39 14 (46.7) 15 (50.0)   12 (30.0) 18 (45.0)  
  ≥ 40 6 (20.0) 7 (23.3)   19 (47.5) 10 (25.0)  
Birthweight (grams) 3281 ± 287 3392 ± 262 0.12 3392 ± 295 3430 ± 295 0.57
Parity    0.49    0.24
 0 28 (93.3) 30 (100)   37 (92.5) 40 (100)  
  ≥ 1 2 (6.7) 0 (0)   3 (7.5) 0 (0)  
Maternal age (years)   0.62    0.25
  < 25 4 (13.3) 3 (10.0)   3 (7.5) 2 (5.0)  
 25–29 14 (46.7) 18 (60.0)   21 (52.5) 21 (52.5)  
 30–34 7 (23.3) 7 (23.3)   16 (40.0) 13 (32.5)  
  ≥ 35 5 (16.7) 2 (6.7)   0 (0) 4 (10.0)  
Pre-pregnancy BMI (kg/m2)    0.73    0.74
  < 18.5 6 (20.0) 4 (13.3)   8 (20.0) 5 (12.5)  
 18.5–24.9 24 (80.0) 25 (83.3)   29 (72.5) 30 (75.0)  
 25.0–29.9 0 (0) 1 (3.3)   3 (7.5) 4 (10.0)  
  ≥ 30 0 (0) 0 (0)   0 (0) 1 (2.5)  
Han ethnicity 29 (96.7) 28 (93.3) 1.00 40 (100) 39 (97.5) 1.00
Male fetus 10 (33.3) 16 (53.3) 0.19 22 (55.0) 23 (57.5) 1.00
Maternal education   0.24    0.09
 High school and below 2 (6.7) 2 (6.7)   8 (20.0) 2 (5.0)  
 College 21 (70.0) 26 (86.7)   31 (77.5) 37 (92.5)  
 Postgraduate 7 (23.3) 2 (6.7)   1 (2.5) 1 (2.5)  
  1. Note: Data presented are mean ± standard deviation, or n (%)
  2. Fisher’s Exact test, or Student’s t test was used to compare the difference of characteristics between VD and CDMR