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Table 3 GLUT1, GLUT3 and HIF-1α gene expression ratios between monochorionic twin pregnancies with selective FGR with (group2) and without (group1) selective FGR twin abnormal umbilical artery Doppler

From: Placental glucose transporter 1 and 3 gene expression in Monochorionic twin pregnancies with selective fetal growth restriction

 

Group 1 twin pregnancies (N = 9)

P value of group 1 twin pregnancies

Group 2 twin pregnancies (N = 6)

P value of group 2 twin pregnancies

GLUT1 gene expression ratio

0.86

0.48

1.13

0.43

GLUT3 gene expression ratio

0.88

0.36

2.23

0.015

HIF-1α gene expression ratio

0.91

0.37

1.65

0.045

  1. Data are expressed as median
  2. An abnormal UA Doppler was defined as persistently absent or reverse end-diastolic flow
  3. The placental GLUT1, GLUT3 and HIF-1α gene expression ratios for the two placental territories in a twin pregnancy pair is presented as the fold changes between the two fetuses in monochorionic twins: ((relative GLUTs (HIF-1α) expression levels of the selective FGR twin)/ (relative GLUTs (HIF-1α) expression levels of the appropriate for gestational age (AGA) twin))
  4. P values were calculated by one sample t test and the test value was set as 1.0
  5. FGR fetal growth restriction