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Table 3 Odds ratio and adjusted odds ratio for obstetric outcomes associated with SARS-CoV-2 exposure in pregnancy

From: The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis

  

Outcomes

Preterm delivery

Spontaneous preterm delivery

PROM

PPROM

NICU admission

Univariate analysis (OR)

 SARS-CoV-2 positive

2.23

1.31

1.72

2.33

4.27

  95% CI

1.41–3.54

0.69–2.39

1.14–2.62

1.06–5.15

2.26–8.05

  p-value

0.001

0.390

0.009

0.031

0.001

Multivariate analysis (aOR)

 SARS-CoV-2 positive

2.12

1.10

1.70

2.26

4.62

  95% CI

1.32–3.36

0.57–2.06

1.11–2.57

0.99–4.98

2.43–8.94

  p-value

0.002

0.760

0.013

0.045

< 0.001

 In Vitro Fertilization

2.37

  95% CI

0.97–5.16

  p-value

0.041

 Miscarriage Risk

2.61

4.19

2.69

  95% CI

0.92–6.42

1.35–10.88

0.42–9.91

  p-value

0.050

0.006

0.198

Ethnicity

 Latin American vs White European

2.11 (1.04–4.09)

 Other Ethnic Groups vs White European

0.38 (0.06–1.27)

  p-value

0.031 and 0.188

 Multiple pregnancy

1.86*10−7

3.72

  95% CI

0.00 – .

1.02–10.73

  p-value

0.981

0.025

 Gestational Hypertensive Disorders

3.63

  95% CI

1.28–8.91

  p-value

0.008

  1. OR Odds Ratio
  2. aOR adjusted Odds Ratio
  3. 95% CI 95% Confidence Interval
  4. PROM Premature Rupture of Membranes at term
  5. PPROM Preterm Premature Rupture of Membranes
  6. NICU Neonatal Intensive Care Unit
  7. Multivariable logistic regression used for each outcome as dependent variable and COVID-19 exposure in pregnancy and known/suspected confounding variables as independent variables (see Methods for details)
  8. -- Variables not included or not held in the multivariate model