Infected Group | Non-Infected Group | p-value | |
---|---|---|---|
Number | 246 | 763 | |
Perinatal outcome | |||
Gestational age at delivery (weeks+days; mean/range) | 38 + 4 (27–42) | 39 + 0 (23–42) | 0.010 |
Type of delivery | |||
Cesarean | 55 (22.4%) | 143 (18.7%) | 0.214 |
Eutocic | 170 (69.1%) | 506 (66.3%) | 0.419 |
Instrumental | 21 (8.5%) | 114 (14.9%) | 0.010 |
Preterm deliveries (< 37 weeks of gestational age) | 34 (13.8%) | 51 (6.7%) | 0.001 |
Spontaneous delivery (including PPROM) | 15 (6.1%) | 36 (4.7%) | 0.390 |
Induced/Elective C-section due to PPROM | 7 (2.8%) | 5 (0.7%) | 0.012 |
Iatrogenic delivery (no PPROM) | 12 (4.9%) | 10 (1.3%) | 0.001 |
Causes of preterm iatrogenic delivery: | |||
COVID-19 mild symptoms | 3/12 | 0/10 | |
Pneumonia | 3/12 | 0/10 | |
Severe preeclampsia | 4/12 | 1/10 | 0.323 |
PROM | 39 (15.8%) | 75 (9.8%) | 0.009 |
PPROM | 11 (4.5%) | 15 (2.0%) | 0.031 |
Gestational age at PPROM (weeks+days; mean/range) | 33 + 5 (28–36) | 33 + 6 (28–36) | 0.610 |
Medical and obstetrical complications | |||
Admitted in ICU | 5 (2.0%) | 2 (0.3%) | 0.011 |
Days in ICU (mean/range) | 9.5 (6–14) | 2 (2–2) | |
Obstetrical complications | |||
Hemorrhagic events | 10 (4.1%) | 34 (4.5%) | 0.794 |
Abruptio placentae | 2 (0.8%) | 1 (0.1%) | 0.149 |
Postpartum hemorrhage | 8 (3.3%) | 33 (4.3%) | 0.459 |
Gestational hypertensive disorders | 11 (4.5%) | 44 (5.8%) | 0.436 |
Severe preeclampsia | 6 (2.4%) | 3 (0.4%) | 0.008 |
Admitted in ICU | 2/6 | 0/3 | |
Invasive ventilation | 0/6 | 0/7 | |
Moderate preeclampsia | 5 (2.0%) | 41 (5.4%) | 0.025 |
Neonatal data | |||
Apgar 5 score < 7 | 5 (2.0%) | 8 (1.1%) | 0.325 |
Umbilical artery pH < 7.10 | 6 (3.0%) | 24 (3.8%) | 0.608 |
Admitted in NICU | 23 (9.3%) | 18 (2.4%) | 0.001 |
Days in NICU (mean/range) | 13.8 (1–48) | 10.7 (2–26) | 0.379 |
Cause of NICU admission: | |||
Prematurity | 15/23 | 12/18 | |
Respiratory distress | 2/23 | 6/18 | |
Neonatal COVID-19 PCR testing within the first 48 h | 196 (79.7%) | 0 (0.0%) | |
Stillbirth | 3 (1.2%) | 1 (0.1%) | 0.047 |
Neonatal mortality | 0 (0.0%) | 1 (0.1%) a | 1.000 |
6 weeks mother follow-up | |||
Mastitis | 1 (0.4%) | 1 (0.1%) | 0.428 |
14 days neonate follow-up | |||
Readmission due to COVID-19 | 0 (0.0%) | 0 (0.0%) |