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Table 4 Meta-analysis of outcomes according to maternal and treatments characteristics

From: Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women - a systematic review and meta-analysis

  Groups ICU Admission Hospital Length of Stay Preterm Birth
Proportion
(95% CI)
Mean (95% CI)a Proportion
(95% CI)
Treatment
 Oxygen support ≤ 0.25 (low) 0.03 (0.00, 0.08) 8.89 (4.31, 13.48) 0.20 (0.10, 0.33)
>  0.25 (high) 0.10 (0.02, 0.21) 9.10 (8.05, 10.15) 0.33 (0.21, 0.46)
 Steroids Not given 0.06 (0.01, 0.15) 7.45 (2.22, 12.69) 0.29 (0.17, 0.42)
Given 0.06 (0.02, 0.11) 9.18 (6.49, 11.86) 0.27 (0.17, 0.37)
 Immunosuppressants Not given 0.03 (0.01, 0.06) 7.75 (5.10, 10.41) 0.26 (0.18, 0.36)
Given 0.24 (0.05, 0.51) 12.37 (4.22, 20.52) 0.35 (0.13, 0.60)
 Hydroxychloroquine ≤ 0.043 (low) 0.02 (0.00, 0.05) 9.95 (6.24, 13.65) 0.30 (0.16, 0.46)
>  0.043 (high) 0.11 (0.04, 0.21) 7.30 (4.22, 10.38) 0.22 (0.15, 0.30)
 Antivirals ≤ 0.25 (low) 0.05 (0.02, 0.09) 8.84 (5.63, 12.05) 0.29 (0.16, 0.44)
>  0.25 (high) 0.07 (0.00, 0.20) 7.38 (4.67, 10.10) 0.25 (0.16, 0.34)
 Zinc/Magnesium Not given 0.06 (0.02, 0.11) 8.34 (5.36, 11.32) 0.26 (0.18, 0.34)
Given 0.07 (0.03, 0.13) NA 0.44 (0.30, 0.58)
 Anticoagulants Not given 0.03 (0.02, 0.05) 8.10 (4.98, 11.23) 0.27 (0.18, 0.38)
Given 0.18 (0.03, 0.40) 9.24 (3.73, 14.74) 0.28 (0.14, 0.44)
 Antibiotics ≤ 0.23 (low) 0.04 (0.01, 0.06) 6.37 (3.49, 9.24) 0.22 (0.13, 0.32)
>  0.23 (high) 0.09 (0.02, 0.20) 10.44 (6.23, 14.65) 0.31 (0.20, 0.44)
 Plasma/Anti-Liver damage Not given 0.06 (0.02, 0.11) 7.74 (5.26, 10.22) 0.28 (0.20, 0.36)
Given 0.04 (0.00, 0.22) 13.99 (9.27, 18.70) 0.17 (0.05, 0.32)
Cesarean section ≤ 0.51 (low) 0.06 (0.02, 0.12) 8.73 (5.11, 12.34) 0.21 (0.13, 0.30)
>  0.51 (high) 0.06 (0.00, 0.15) 7.95 (5.45, 10.45) 0.33 (0.20, 0.46)
Symptomatic ≤ 0.94 (low) 0.04 (0.01, 0.08) 7.62 (3.80, 11.45) 0.18 (0.15, 0.22)
>  0.94 (high) 0.10 (0.02, 0.22) 7.85 (5.17, 10.53) 0.38 (0.23, 0.54)
Comorbidities
 Diabetes mellitus ≤ 0.06 (low) 0.07 (0.02, 0.13) 8.32 (5.08, 11.55) 0.21 (0.14, 0.29)
>  0.06 (high) 0.08 (0.00, 0.22) 8.62 (4.42, 12.82) 0.39 (0.19, 0.61)
 Hypertension ≤ 0.03 (low) 0.11 (0.01, 0.27) 10.81 (6.60, 15.01) 0.27 (0.12, 0.44)
>  0.03 (high) 0.04 (0.02, 0.07) 6.76 (4.54, 8.98) 0.32 (0.18, 0.47)
 Asthma ≤ 0.034 (low) 0.07 (0.00, 0.22) 9.97 (5.63, 14.30) 0.35 (0.19, 0.53)
>  0.034 (high) 0.07 (0.03, 0.13) 7.28 (3.95, 10.62) 0.24 (0.11, 0.40)
 Obesity ≤ 0.10 (low) 0.04 (0.01, 0.08) 7.71 (3.58, 11.85) 0.42 (0.10, 0.78)
>  0.10 (high) 0.13 (0.03, 0.29) 8.25 (4.37, 12.13) 0.33 (0.15, 0.53)
  1. aWeighted mean reported; ICU intensive care unit, CI confidence interval, NA not available; bold values indicate a significant presence (at least 5%) of the condition relative to their average value