Table 4 Meta-analysis of outcomes according to maternal and treatments characteristics
|  | Groups | ICU Admission | Hospital Length of Stay | Preterm Birth |
|---|---|---|---|---|
Proportion (95% CI) | Mean (95% CI)a | Proportion (95% CI) | ||
Treatment | ||||
 Oxygen support | ≤ 0.25 (low) | 0.03 (0.00, 0.08) | 8.89 (4.31, 13.48) | 0.20 (0.10, 0.33) |
>  0.25 (high) | 0.10 (0.02, 0.21) | 9.10 (8.05, 10.15) | 0.33 (0.21, 0.46) | |
 Steroids | Not given | 0.06 (0.01, 0.15) | 7.45 (2.22, 12.69) | 0.29 (0.17, 0.42) |
Given | 0.06 (0.02, 0.11) | 9.18 (6.49, 11.86) | 0.27 (0.17, 0.37) | |
 Immunosuppressants | Not given | 0.03 (0.01, 0.06) | 7.75 (5.10, 10.41) | 0.26 (0.18, 0.36) |
Given | 0.24 (0.05, 0.51) | 12.37 (4.22, 20.52) | 0.35 (0.13, 0.60) | |
 Hydroxychloroquine | ≤ 0.043 (low) | 0.02 (0.00, 0.05) | 9.95 (6.24, 13.65) | 0.30 (0.16, 0.46) |
>  0.043 (high) | 0.11 (0.04, 0.21) | 7.30 (4.22, 10.38) | 0.22 (0.15, 0.30) | |
 Antivirals | ≤ 0.25 (low) | 0.05 (0.02, 0.09) | 8.84 (5.63, 12.05) | 0.29 (0.16, 0.44) |
>  0.25 (high) | 0.07 (0.00, 0.20) | 7.38 (4.67, 10.10) | 0.25 (0.16, 0.34) | |
 Zinc/Magnesium | Not given | 0.06 (0.02, 0.11) | 8.34 (5.36, 11.32) | 0.26 (0.18, 0.34) |
Given | 0.07 (0.03, 0.13) | NA | 0.44 (0.30, 0.58) | |
 Anticoagulants | Not given | 0.03 (0.02, 0.05) | 8.10 (4.98, 11.23) | 0.27 (0.18, 0.38) |
Given | 0.18 (0.03, 0.40) | 9.24 (3.73, 14.74) | 0.28 (0.14, 0.44) | |
 Antibiotics | ≤ 0.23 (low) | 0.04 (0.01, 0.06) | 6.37 (3.49, 9.24) | 0.22 (0.13, 0.32) |
>  0.23 (high) | 0.09 (0.02, 0.20) | 10.44 (6.23, 14.65) | 0.31 (0.20, 0.44) | |
 Plasma/Anti-Liver damage | Not given | 0.06 (0.02, 0.11) | 7.74 (5.26, 10.22) | 0.28 (0.20, 0.36) |
Given | 0.04 (0.00, 0.22) | 13.99 (9.27, 18.70) | 0.17 (0.05, 0.32) | |
Cesarean section | ≤ 0.51 (low) | 0.06 (0.02, 0.12) | 8.73 (5.11, 12.34) | 0.21 (0.13, 0.30) |
>  0.51 (high) | 0.06 (0.00, 0.15) | 7.95 (5.45, 10.45) | 0.33 (0.20, 0.46) | |
Symptomatic | ≤ 0.94 (low) | 0.04 (0.01, 0.08) | 7.62 (3.80, 11.45) | 0.18 (0.15, 0.22) |
>  0.94 (high) | 0.10 (0.02, 0.22) | 7.85 (5.17, 10.53) | 0.38 (0.23, 0.54) | |
Comorbidities | ||||
 Diabetes mellitus | ≤ 0.06 (low) | 0.07 (0.02, 0.13) | 8.32 (5.08, 11.55) | 0.21 (0.14, 0.29) |
>  0.06 (high) | 0.08 (0.00, 0.22) | 8.62 (4.42, 12.82) | 0.39 (0.19, 0.61) | |
 Hypertension | ≤ 0.03 (low) | 0.11 (0.01, 0.27) | 10.81 (6.60, 15.01) | 0.27 (0.12, 0.44) |
>  0.03 (high) | 0.04 (0.02, 0.07) | 6.76 (4.54, 8.98) | 0.32 (0.18, 0.47) | |
 Asthma | ≤ 0.034 (low) | 0.07 (0.00, 0.22) | 9.97 (5.63, 14.30) | 0.35 (0.19, 0.53) |
>  0.034 (high) | 0.07 (0.03, 0.13) | 7.28 (3.95, 10.62) | 0.24 (0.11, 0.40) | |
 Obesity | ≤ 0.10 (low) | 0.04 (0.01, 0.08) | 7.71 (3.58, 11.85) | 0.42 (0.10, 0.78) |
>  0.10 (high) | 0.13 (0.03, 0.29) | 8.25 (4.37, 12.13) | 0.33 (0.15, 0.53) | |