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Table 2 Overall estimates of maternal characteristics, treatment profile, and outcomes

From: Current trends and geographical differences in therapeutic profile and outcomes of COVID-19 among pregnant women - a systematic review and meta-analysis

  Case series Case reports P-value
Proportion (95% CI) Proportion (95% CI)
Maternal Characteristics
 Age (years) mean (95% CI) 30.60 (28.90, 32.40)a 31.10 (29.97, 32.24) 0.359
 BMI (Kg/m2) mean (95% CI) 29.40 (27.30, 31.70)a 35.81 (32.04, 39.57) <  0.001
 Gestational age (weeks) mean (95% CI) 31.30 (28.80, 33.80)a 32.70 (31.31, 34.24) 0.050
Symptomatic presentation 0.89 (0.75, 0.98) 0.89 (0.78, 0.95) 0.006
Comorbidities
 Diabetes mellitus 0.04 (0.03, 0.07) 0.23 (0.12, 0.39) <  0.001
 Hypertension 0.04 (0.02, 0.07) 0.09 (0.03, 0.22) 0.283
 Asthma 0.04 (0.02, 0.06) 0.09 (0.03, 0.22) 0.131
 Obesity 0.09 (0.04, 0.15) 0.29 (0.16, 0.46) <  0.001
Treatment
 Oxygen support 0.33 (0.20, 0.47) 0.53 (0.40, 0.66) <  0.001
 Steroids 0.06 (0.00, 0.19) 0.44 (0.31, 0.57) <  0.001
 Immunosuppressants 0.01 (0.00, 0.03) 0.10 (0.04, 0.20) 0.004
 Hydroxychloroquine 0.10 (0.03, 0.19) 0.26 (0.16, 0.38) 0.082
 Antivirals 0.33 (0.18, 0.49) 0.45 (0.32, 0.58) < 0.001
 Zinc/Magnesium 0.02 (0.00, 0.14) 0.21 (0.12, 0.34) 0.007
 Anticoagulants 0.03 (0.00, 0.07) 0.12 (0.05, 0.23) 0.031
 Antibiotics 0.36 (0.21, 0.52) 0.64 (0.51, 0.76) <  0.001
 Plasma therapy/Anti-liver damage 0.02 (0.00, 0.06) 0.14 (0.07, 0.26) <  0.001
 Mechanical ventilation 0.03 (0.01, 0.07) 0.35 (0.23, 0.49) <  0.001
Maternal & Pregnancy Outcomes
 ICU admission 0.06 (0.02, 0.10) 0.43 (0.31, 0.57) < 0.001
 Hospital length of stay (days) mean (95% CI) 8.47 (5.96, 10.97)a 14.6 (12.0, 17.2) <  0.001
 Maternal death 0.003 (0.00, 0.02) 0.05 (0.01, 0.13) 0.108
 Cesarean section 0.62 (0.54, 0.71) 0.69 (0.56, 0.80) 0.085
 Fetal demise < 1% 0.08 (0.03, 0.19) 0.003
 Neonatal death < 1% 0.02 (0.00, 0.08) 0.143
 Premature birth 0.26 (0.19, 0.34) 0.50 (0.37, 0.63) <  0.001
  1. aWeighted mean reported; I2 % measure of heterogeneity, CI confidence interval, ICU intensive care unit, NA not applicable, BMI body mass index